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NCT01258933 · ClinicalTrials.gov registry record · Phase 2
Ofatumumab for Minimal Residual Disease (MRD) and Maintenance Therapy
A Phase 2 study, sponsored by M.D. Anderson Cancer Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 4
- Enrollment target
NCT01258933: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.
NCT01258933 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 4 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01258933, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 4 participants
- Enrollment target
Study Summary
The goal of this clinical research study is to find out if ofatumumab can control CLL or SLL that is left after chemotherapy or chemoimmunotherapy. The safety of the drug will also be studied.
Primary Outcome
Response assessment according to 2008 International Working Group for CLL (IWCLL), prior to 9th dose of ofatumumab (prior to first bimonthly dose). Responses of (complete remission (CR) conversion to minimal residual disease (MRD) negative, partial remission (PR) conversion to nodular partial remission nPR or CR, and nPR conversion to complete remission (CR)) evaluated by physical examination, CBC, CT of chest, abdomen, pelvis, and bone marrow aspirate and biopsy with evaluation of residual dise
Interventions
- DRUG Ofatumumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2011-07-06 |
| Est. Completion | 2024-10-18 |
| Phase | Phase 2 |
Why NCT01258933 stopped before completion
NCT01258933 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Ofatumumab is the first listed.
NCT01258933 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01258933 about?
NCT01258933 is a clinical study titled "Ofatumumab for Minimal Residual Disease (MRD) and Maintenance Therapy". The goal of this clinical research study is to find out if ofatumumab can control CLL or SLL that is left after chemotherapy or chemoimmunotherapy. The safety of the drug will also be studied.
What is the current status of trial NCT01258933?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2011-07-06. Estimated completion is 2024-10-18.
What interventions are being tested in trial NCT01258933?
The interventions under investigation include: Ofatumumab (DRUG).
Who is sponsoring clinical trial NCT01258933?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01258933's enrollment target sits among peer trials
4 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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