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NCT01248221 · ClinicalTrials.gov registry record · NA

Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT)

A NA study, sponsored by Mayo Clinic.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT01248221: Completed NA study, sponsored by Mayo Clinic.

NCT01248221 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01248221, a NA study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

The purpose of this study is to compare stomach emptying using 13C-Spirulina platensis breath test and scintigraphy in healthy subjects and subjects with dyspepsia. Subjects will eat a standard meal of 2 scrambled eggs, a slice of wheat toast and 8 ounces of skim milk. The eggs will be double labeled with Technetium-99m (99mTc) sulfur colloid and 13C-Spirulina platensis. Scintigraphy is a diagnostic technique in which a two-dimensional picture of internal body tissue is produced through the detection of radiation emitted by a radioactive substance administered into the body. The location of a standard meal in the digestive system will be measured by images of the 99mTc sulfur colloid taken at periodic intervals before and after the standard meal. The 99mTc Sulfur Colloid is approved by the FDA for use in medical diagnostic procedures. Spirulina platensis is blue - green algae, which is very similar to the naturally occurring spirulina sold in health food stores as a dietary supplement. The spirulina platensis has been labeled with the 13C stable isotope. 13C stable isotope labeling is inherently safe as 1.1% of all carbon in our bodies and in the food we eat is 13C. The presence of the 13C will be measured by breath samples at periodic intervals before and after a standard meal. The FDA considers 13C-Spirulina platensis to be investigational for the purposes of this study.

Primary Outcome

Gastric emptying half time is the time for half of the ingested solids to leave the stomach. This value was measured by standard 99m Tc scintigraphy.

Interventions

  • DRUG [13C]-Spirulina platensis and 99mTc sulfur colloid

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2010-12
Est. Completion 2011-12
Phase NA
Mayo Clinic

2,844 total trials

What the finished NCT01248221 record still lists

NCT01248221 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which [13C]-Spirulina platensis and 99mTc sulfur colloid is the first listed.

NCT01248221 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01248221 about?

NCT01248221 is a clinical study titled "Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT)". The purpose of this study is to compare stomach emptying using 13C-Spirulina platensis breath test and scintigraphy in healthy subjects and subjects with dyspepsia. Subjects will eat a standard meal of 2 scrambled eggs, a slice of wheat toast and 8 ounces of skim milk. The eggs will be double label...

What is the current status of trial NCT01248221?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2010-12. Estimated completion is 2011-12.

What interventions are being tested in trial NCT01248221?

The interventions under investigation include: [13C]-Spirulina platensis and 99mTc sulfur colloid (DRUG).

Who is sponsoring clinical trial NCT01248221?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01248221's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01248221, the US trial registry maintained by the National Library of Medicine. NCT01248221 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.