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NCT01245595 · ClinicalTrials.gov registry record · NA
Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 144
- Enrollment target
NCT01245595: Completed NA study, sponsored by Stanford University.
NCT01245595 is a NA study that has completed, run by Stanford University. The registered enrollment target is 144 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01245595, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 144 participants
- Enrollment target
Study Summary
Children with congenital heart defects often need cardiac surgery with cardiopulmonary bypass (the "heart-lung machine"). Approximately 35 to 50% of these children will have "acute kidney injury," or damage to the kidneys, after the procedure. We currently have few medications to prevent this kidney injury. The hypothesis of this study is that giving aminophylline after heart surgery can decrease the acute kidney injury.
Primary Outcome
Acute Kidney Injury measured by Kidney Diseases: Improving Global Outcomes (KDIGO) AKI Serum Creatinine criteria; KDIGO Stage is a measure of acute kidney injury.
Interventions
- DRUG Placebo
- DRUG Aminophylline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2010-11 |
| Est. Completion | 2014-05 |
| Phase | NA |
What the finished NCT01245595 record still lists
NCT01245595 is an interventional study that assigns participants to a tested intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01245595 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01245595 about?
NCT01245595 is a clinical study titled "Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery". Children with congenital heart defects often need cardiac surgery with cardiopulmonary bypass (the "heart-lung machine"). Approximately 35 to 50% of these children will have "acute kidney injury," or damage to the kidneys, after the procedure. We currently have few medications to prevent this kidney...
What is the current status of trial NCT01245595?
This trial is currently completed. It is a NA study. The enrollment target is 144 participants. The study started on 2010-11. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01245595?
The interventions under investigation include: Placebo (DRUG), Aminophylline (DRUG).
Who is sponsoring clinical trial NCT01245595?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01245595's enrollment target sits among peer trials
144 706th of 2000 higher than 1,290 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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