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NCT01245205 · ClinicalTrials.gov registry record · Phase 1

Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast Cancer

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
28
Enrollment target

NCT01245205: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT01245205 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 28 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01245205, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
28 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and the best dose of Akt inhibitor MK2206 and lapatinib ditosylate in treating patients with solid tumors or breast cancer that has spread to other places in the body. Akt inhibitor MK2206 and lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER pharmacological study
  • DRUG lapatinib ditosylate
  • DRUG Akt inhibitor MK2206

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2010-11
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01245205

The ClinicalTrials.gov registry entry for NCT01245205 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT01245205 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01245205 about?

NCT01245205 is a clinical study titled "Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast Cancer". This phase I trial studies the side effects and the best dose of Akt inhibitor MK2206 and lapatinib ditosylate in treating patients with solid tumors or breast cancer that has spread to other places in the body. Akt inhibitor MK2206 and lapatinib ditosylate may stop the growth of tumor cells by bloc...

What is the current status of trial NCT01245205?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2010-11.

What interventions are being tested in trial NCT01245205?

The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), lapatinib ditosylate (DRUG), Akt inhibitor MK2206 (DRUG).

Who is sponsoring clinical trial NCT01245205?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.