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NCT01239316 · ClinicalTrials.gov registry record · Phase 2

Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma

A Phase 2 study of Recurrent Childhood Medulloblastoma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
12
Enrollment target
12
Study locations

NCT01239316 is a Phase 2 study of Recurrent Childhood Medulloblastoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 12 participants, below the 54-participant average among 3 other Recurrent Childhood Medulloblastoma trials with a reported enrollment target (78% lower). The trial reports 12 study locations across 10 states.

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The verdict

NCT01239316, a Phase 2 study of Recurrent Childhood Medulloblastoma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
12 participants
Enrollment target
12
Study locations

Study Summary

This phase II trial studies how well vismodegib works in treating younger patients with recurrent or refractory medulloblastoma. Vismodegib may slow the growth of tumor cells.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Vismodegib
  • OTHER Pharmacological Study

Study Locations (12)

California

  • Children's Hospital Los Angeles - Los Angeles
  • Lucile Packard Children's Hospital Stanford University - Palo Alto

Pennsylvania

  • Children's Hospital of Philadelphia - Philadelphia
  • Children's Hospital of Pittsburgh of UPMC - Pittsburgh

District of Columbia

  • Children's National Medical Center - Washington D.C.

Illinois

  • Lurie Children's Hospital-Chicago - Chicago

Maryland

  • National Cancer Institute Pediatric Oncology Branch - Bethesda

New York

  • Memorial Sloan-Kettering Cancer Center - New York

North Carolina

  • Duke University Medical Center - Durham

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2010-11
Est. Completion 2015-08
Phase Phase 2

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01239316

The ClinicalTrials.gov registry entry for NCT01239316 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 54-participant average among 3 other Recurrent Childhood Medulloblastoma trials with a reported enrollment target (78% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Recurrent Childhood Medulloblastoma appearing as the primary indexed condition, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT01239316 reports 12 study locations spanning 10 distinct geographic areas - top geographies include California, Pennsylvania, District of Columbia.

Frequently Asked Questions

What is clinical trial NCT01239316 about?

NCT01239316 is a clinical study titled "Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma". This phase II trial studies how well vismodegib works in treating younger patients with recurrent or refractory medulloblastoma. Vismodegib may slow the growth of tumor cells.

What is the current status of trial NCT01239316?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2010-11. Estimated completion is 2015-08.

What conditions does trial NCT01239316 study?

This clinical trial studies the following conditions: Recurrent Childhood Medulloblastoma.

What interventions are being tested in trial NCT01239316?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Vismodegib (DRUG), Pharmacological Study (OTHER).

Who is sponsoring clinical trial NCT01239316?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01239316 being conducted?

This trial has 12 study locations across California, District of Columbia, Illinois, Maryland, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.