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NCT01231386 · ClinicalTrials.gov registry record
MIRNA Profiling of Breast Cancer in Patients Undergoing Neoadjuvant or Adjuvant Treatment for Locally Advanced & Inflammatory Breast Cancer
A clinical trial, sponsored by City of Hope Medical Center.
- Completed
- Registry status
- 199
- Enrollment target
NCT01231386 is a clinical trial that has completed, run by City of Hope Medical Center. The registered enrollment target is 199 participants.
The verdict
NCT01231386 has completed, sponsored by City of Hope Medical Center.
- COMPLETED
- Registry status
- 199 participants
- Enrollment target
Study Summary
MicroRNAs (MiRNAs) regulate the translation of RNAs and are implicated in cell proliferation and renewal both under physiologically normal as well as in malignant conditions. Dysregulation of specific miRNAs may be associated with either gaining oncogenic or loosing tumor suppressing functions. MiRNA dysregulation has been implicated in breast cancer tumorigenic (stem cell) and non-tumorigenic development. Therefore, miRNA profiling of treatment naïve and treatment-exposed breast tumors and sequential samples of blood/serum will allow for identification of miRNA markers of prognosis and as indicators and potential targets for personalized therapies. In this proposal, specimens from patients treated in the clinical breast cancer program on already existing protocols (IRB 05091 and 05015) will be characterized by Dr. Rossi's laboratory and collaborators, and the information gained will be applied to develop specific therapies.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 199 participants |
| Start Date | 2009-11 |
| Est. Completion | 2019-05-20 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01231386
The ClinicalTrials.gov registry entry for NCT01231386 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 199 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01231386 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01231386 about?
NCT01231386 is a clinical study titled "MIRNA Profiling of Breast Cancer in Patients Undergoing Neoadjuvant or Adjuvant Treatment for Locally Advanced & Inflammatory Breast Cancer". MicroRNAs (MiRNAs) regulate the translation of RNAs and are implicated in cell proliferation and renewal both under physiologically normal as well as in malignant conditions. Dysregulation of specific miRNAs may be associated with either gaining oncogenic or loosing tumor suppressing functions. MiRN...
What is the current status of trial NCT01231386?
This trial is currently completed. The enrollment target is 199 participants. The study started on 2009-11. Estimated completion is 2019-05-20.
Who is sponsoring clinical trial NCT01231386?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
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