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NCT01230424 · ClinicalTrials.gov registry record · Phase 4
Effect of Steroid Injections in a Knee With Osteoarthritis
A Phase 4 study of Osteoarthritis (OA) of the Knee, sponsored by Tufts Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 140
- Enrollment target
- 2
- Study locations
NCT01230424 is a Phase 4 study of Osteoarthritis (OA) of the Knee that has completed, run by Tufts Medical Center. The registered enrollment target is 140 participants, below the 1,396-participant average among 8 other Osteoarthritis (OA) of the Knee trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT01230424, a Phase 4 study of Osteoarthritis (OA) of the Knee, has completed, sponsored by Tufts Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 140 participants
- Enrollment target
- 2
- Study locations
Study Summary
A steroid (triamcinolone) 40 mg will be compared to placebo in a randomized placebo-controlled clinical trial testing the effect of this steroid versus placebo given into the study knee joint that has osteoarthritis (OA). The knee injection will be given once every 12 weeks over two years for a total of eight knee injections. How well each participant tolerates each injection and all the injections over time will be assessed. The safety of getting a knee injection every 12 weeks will be assessed by collecting reported adverse effects, knee examinations, and clinical laboratory tests. Participants will complete questionnaires, X-ray, MRIs, and bone density tests as part of this study.
Conditions Studied
Interventions
- DRUG Triamcinolone Acetonide
- DRUG 0.9% Sodium Chloride Injection as Placebo
Study Locations (2)
Massachusetts
- Tufts Medical Center / Division of Rheumatology - Boston
- Tufts Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2011-03 |
| Est. Completion | 2015-01 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01230424
The ClinicalTrials.gov registry entry for NCT01230424 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,396-participant average among 8 other Osteoarthritis (OA) of the Knee trials with a reported enrollment target (90% lower). The listed sponsor is Tufts Medical Center, which has 169 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Osteoarthritis (OA) of the Knee appearing as the primary indexed condition, and to 2 interventions - of which Triamcinolone Acetonide is the first listed.
NCT01230424 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01230424 about?
NCT01230424 is a clinical study titled "Effect of Steroid Injections in a Knee With Osteoarthritis". A steroid (triamcinolone) 40 mg will be compared to placebo in a randomized placebo-controlled clinical trial testing the effect of this steroid versus placebo given into the study knee joint that has osteoarthritis (OA). The knee injection will be given once every 12 weeks over two years for a tota...
What is the current status of trial NCT01230424?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 140 participants. The study started on 2011-03. Estimated completion is 2015-01.
What conditions does trial NCT01230424 study?
This clinical trial studies the following conditions: Osteoarthritis (OA) of the Knee.
What interventions are being tested in trial NCT01230424?
The interventions under investigation include: Triamcinolone Acetonide (DRUG), 0.9% Sodium Chloride Injection as Placebo (DRUG).
Who is sponsoring clinical trial NCT01230424?
This trial is sponsored by Tufts Medical Center, which has 169 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01230424 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.