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NCT01229514 · ClinicalTrials.gov registry record
Functional Magnetic Resonance Imaging (fMRI) Findings in Children With Early Exposure to General Anesthesia
A clinical trial, sponsored by Nationwide Children's Hospital.
- Completed
- Registry status
- 30
- Enrollment target
NCT01229514 is a clinical trial that has completed, run by Nationwide Children's Hospital. The registered enrollment target is 30 participants.
The verdict
NCT01229514 has completed, sponsored by Nationwide Children's Hospital.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
Study Summary
General anesthetic medications have been shown to cause neuronal cell death in the brains of infant rodents. Ethanol and general anesthetics both act on NMDA and GABA receptors,and appear to have similar mechanisms of toxicity in the immature rodent brain. Functional MRI (fMRI) is a technique developed for mapping brain activation and has been utilized to examine how the brains of children with a history of early exposure to ethanol function differently from children without such a history. This study will utilize fMRI to look for specific changes in brain activation patterns in children with a history of early exposure to general anesthesia, as compared to children without such exposure.
Interventions
- OTHER fMRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2008-10 |
| Est. Completion | 2011-06 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01229514
The ClinicalTrials.gov registry entry for NCT01229514 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nationwide Children's Hospital, which has 188 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which fMRI is the first listed.
NCT01229514 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01229514 about?
NCT01229514 is a clinical study titled "Functional Magnetic Resonance Imaging (fMRI) Findings in Children With Early Exposure to General Anesthesia". General anesthetic medications have been shown to cause neuronal cell death in the brains of infant rodents. Ethanol and general anesthetics both act on NMDA and GABA receptors,and appear to have similar mechanisms of toxicity in the immature rodent brain. Functional MRI (fMRI) is a technique develo...
What is the current status of trial NCT01229514?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2008-10. Estimated completion is 2011-06.
What interventions are being tested in trial NCT01229514?
The interventions under investigation include: fMRI (OTHER).
Who is sponsoring clinical trial NCT01229514?
This trial is sponsored by Nationwide Children's Hospital, which has 188 total clinical trials registered on ClinicalTrials.gov.
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