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NCT01225393 · ClinicalTrials.gov registry record · Phase 2
A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis
A Phase 2 study, sponsored by Genentech.
- Completed
- Registry status
- Phase 2
- Development phase
- 211
- Enrollment target
NCT01225393: Completed Phase 2 study, sponsored by Genentech.
NCT01225393 is a Phase 2 study that has completed, run by Genentech. The registered enrollment target is 211 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01225393, a Phase 2 study, has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 211 participants
- Enrollment target
Study Summary
This is a Phase II, randomized, double-blind, placebo-controlled, parallel-group, multicenter study enrolling patients with active rheumatoid arthritis (RA).
Interventions
- DRUG placebo
- DRUG methotrexate
- DRUG adalimumab
- DRUG leflunomide
- DRUG MLTA3698A
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 211 participants |
| Start Date | 2010-11 |
| Phase | Phase 2 |
What the finished NCT01225393 record still lists
NCT01225393 is an interventional study that assigns participants to a tested intervention. The registered 211 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% higher).
The record links to 0 conditions, and to 5 interventions - of which placebo is the first listed.
NCT01225393 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01225393 about?
NCT01225393 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis". This is a Phase II, randomized, double-blind, placebo-controlled, parallel-group, multicenter study enrolling patients with active rheumatoid arthritis (RA).
What is the current status of trial NCT01225393?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 211 participants. The study started on 2010-11.
What interventions are being tested in trial NCT01225393?
The interventions under investigation include: placebo (DRUG), methotrexate (DRUG), adalimumab (DRUG), leflunomide (DRUG), MLTA3698A (DRUG).
Who is sponsoring clinical trial NCT01225393?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01225393's enrollment target sits among peer trials
211 290th of 2000 higher than 1,711 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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