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NCT01221441 · ClinicalTrials.gov registry record · Phase 2
Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee
A Phase 2 study, sponsored by Kolon TissueGene.
- Completed
- Registry status
- Phase 2
- Development phase
- 102
- Enrollment target
NCT01221441: Completed Phase 2 study, sponsored by Kolon TissueGene.
NCT01221441 is a Phase 2 study that has completed, run by Kolon TissueGene. The registered enrollment target is 102 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01221441, a Phase 2 study, has completed, sponsored by Kolon TissueGene.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 102 participants
- Enrollment target
Study Summary
The purpose of this study is to see if we can safely regenerate cartilage without invasive surgery using a biologic product called TissueGene-C.
Primary Outcome
Symptoms, pain and function of the knee joint determined and scored using the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation (Total Score, range 0-100 with higher scores better). Linear mixed model used for analysis.
Interventions
- DRUG Normal Saline
- BIOLOGICAL TissueGene-C
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2011-05 |
| Est. Completion | 2014-10 |
| Phase | Phase 2 |
What the finished NCT01221441 record still lists
NCT01221441 is an interventional study that assigns participants to a tested intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (23% lower).
The record links to 0 conditions, and to 2 interventions - of which Normal Saline is the first listed.
NCT01221441 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01221441 about?
NCT01221441 is a clinical study titled "Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee". The purpose of this study is to see if we can safely regenerate cartilage without invasive surgery using a biologic product called TissueGene-C.
What is the current status of trial NCT01221441?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 102 participants. The study started on 2011-05. Estimated completion is 2014-10.
What interventions are being tested in trial NCT01221441?
The interventions under investigation include: Normal Saline (DRUG), TissueGene-C (BIOLOGICAL).
Who is sponsoring clinical trial NCT01221441?
This trial is sponsored by Kolon TissueGene, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01221441's enrollment target sits among peer trials
102 668th of 2000 higher than 1,329 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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