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NCT01202162 · ClinicalTrials.gov registry record · NA
A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough
A NA study, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 85
- Enrollment target
NCT01202162 is a NA study that has completed, run by Northwestern University. The registered enrollment target is 85 participants.
The verdict
NCT01202162, a NA study, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 85 participants
- Enrollment target
Study Summary
Goals for ambulatory surgery include providing optimal surgical conditions while ensuring a rapid early recovery without side effect. Dexter et al1 concluded in a meta-analysis that Desflurane can reduce the extubation time when compared to Sevoflurane. This potential benefit of Desflurane can be especially attractive in short ambulatory cases performed with general anesthesia with a laryngeal mask airway. Although some studies have not shown a difference on perioperative cough and laryngospasm between Desflurane and Sevoflurane at clinically relevant doses.It has been reported in the literature that Desflurane causes cough4 and many providers avoid using Desflurane with a LMA (laryngeal mask airway) in the ambulatory setting. In this study we will also evaluate, as a secondary outcome, the presence and severity of perioperative cough and laryngospasm. Previous investigators have demonstrated a more rapid resumption of normal daily activities after ambulatory surgery in patients anesthetized with Desflurane when compared with Sevoflurane.these investigators suggested a better quality of recovery when Desflurane is used probably due to a lower lipid solubility of Desflurane. We will also evaluate quality of recovery as a secondary outcome using a validated instrument. Significance: 1. A more rapid awakening, especially, in a fast and high turnover cases that are performed with LMA can lead to a more cost effective utilization of operating room time 2. It has been reported that Desflurane causes more cough than Sevoflurane and Anesthesiologists avoid using Desflurane with LMA cases, this study will reinforce that there is no difference.
Interventions
- DRUG Desflurane
- DRUG Administration of Sevoflurane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 85 participants |
| Start Date | 2010-02 |
| Est. Completion | 2012-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01202162
The ClinicalTrials.gov registry entry for NCT01202162 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 85 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Desflurane is the first listed.
NCT01202162 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01202162 about?
NCT01202162 is a clinical study titled "A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough". Goals for ambulatory surgery include providing optimal surgical conditions while ensuring a rapid early recovery without side effect. Dexter et al1 concluded in a meta-analysis that Desflurane can reduce the extubation time when compared to Sevoflurane. This potential benefit of Desflurane can be es...
What is the current status of trial NCT01202162?
This trial is currently completed. It is a NA study. The enrollment target is 85 participants. The study started on 2010-02. Estimated completion is 2012-03.
What interventions are being tested in trial NCT01202162?
The interventions under investigation include: Desflurane (DRUG), Administration of Sevoflurane (DRUG).
Who is sponsoring clinical trial NCT01202162?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
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