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NCT01199991 · ClinicalTrials.gov registry record
Comparison of Xtreme CT and DXA Bone Densitometry
A clinical trial, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- 84
- Enrollment target
NCT01199991: Clinical Trial study, sponsored by Massachusetts General Hospital.
NCT01199991 is a clinical trial that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 84 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01199991 was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- 84 participants
- Enrollment target
Study Summary
Dual-energy x-ray absorptiometry (DXA) is currently the most widely used tool for determining bone density. However, most experts consider DXA an imperfect and intermediate technology. DXA is subject to artifact from arthritis and body composition, and also cannot account for geometric or material properties of bone which are also important components of bone strength. Xtreme CT (high-resolution peripheral quantitative computed tomography, HR-pQCT) is a new technology with dramatically improved spatial resolution. It is able to define bones' cortical and trabecular surfaces in a three-dimensional manner, and therefore provides information on bone microarchitecture as well as bone density. As such, it may provide new information about characteristics of bone strength. The purpose of this study is to compare Xtreme CT to DXA measurements of bone density, and also to generate a normative database of healthy young adults. This cross-sectional study involves a single visit where both Xtreme CT and DXA measurements will be obtained for a single time-point. This normative database will allow us to generate clinically relevant comparisons between the two imaging technologies.
Primary Outcome
Bone imaging of forearm and lower leg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2010-08 |
| Est. Completion | 2018-06-29 |
Why NCT01199991 stopped before completion
NCT01199991 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 84 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01199991 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01199991 about?
NCT01199991 is a clinical study titled "Comparison of Xtreme CT and DXA Bone Densitometry". Dual-energy x-ray absorptiometry (DXA) is currently the most widely used tool for determining bone density. However, most experts consider DXA an imperfect and intermediate technology. DXA is subject to artifact from arthritis and body composition, and also cannot account for geometric or material p...
What is the current status of trial NCT01199991?
This trial is currently terminated. The enrollment target is 84 participants. The study started on 2010-08. Estimated completion is 2018-06-29.
Who is sponsoring clinical trial NCT01199991?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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