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NCT01195883 · ClinicalTrials.gov registry record · NA

Effect of Goal-directed Crystalloid Versus Colloid Administration on Major Postoperative Morbidity

A NA study, sponsored by The Cleveland Clinic.

Completed
Registry status
NA
Development phase
1,102
Enrollment target

NCT01195883: Completed NA study, sponsored by The Cleveland Clinic.

NCT01195883 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 1,102 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (22% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01195883, a NA study, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
NA
Development phase
1,102 participants
Enrollment target

Study Summary

A trial in which patients having open abdominal surgery are randomized to receive either crystalloids or colloids intraoperatively, guided by esophageal Doppler. The investigators test the primary hypothesis that goal-directed colloid administration during elective abdominal surgery decreases a composite of postoperative complications within 30 days of surgery.

Primary Outcome

Any of the following major complications: (1) Cardiac (Acute heart failure/Myocardial infarction/Ventricular arrhythmia); (2) pulmonary (embolism/edema/respiratory failure/pneumonia/pleural effusion); (3) gastrointestinal (bowel and surgical anastomosis stricture or anastomotic leak/internal or external fistulas/peritoneal effusions); (4) Renal (requiring dialysis); (5) Infectious (deep or organ space surgical site infection / sepsis); and (6) Coagulation (bleeding).

Interventions

  • DRUG Crystalloid
  • DRUG Colloid

Trial Details

FieldValue
Enrollment Target 1,102 participants
Start Date 2010-11
Est. Completion 2017-10-20
Phase NA
The Cleveland Clinic

688 total trials

What the finished NCT01195883 record still lists

NCT01195883 is an interventional study that assigns participants to a tested intervention. Its 1,102 participants enrollment target places it among the larger protocols in the corpus, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (22% lower).

The record links to 0 conditions, and to 2 interventions - of which Crystalloid is the first listed.

NCT01195883 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01195883 about?

NCT01195883 is a clinical study titled "Effect of Goal-directed Crystalloid Versus Colloid Administration on Major Postoperative Morbidity". A trial in which patients having open abdominal surgery are randomized to receive either crystalloids or colloids intraoperatively, guided by esophageal Doppler. The investigators test the primary hypothesis that goal-directed colloid administration during elective abdominal surgery decreases a comp...

What is the current status of trial NCT01195883?

This trial is currently completed. It is a NA study. The enrollment target is 1,102 participants. The study started on 2010-11. Estimated completion is 2017-10-20.

What interventions are being tested in trial NCT01195883?

The interventions under investigation include: Crystalloid (DRUG), Colloid (DRUG).

Who is sponsoring clinical trial NCT01195883?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01195883's enrollment target sits among peer trials

1,102 93rd of 2000 higher than 1,908 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01195883, the US trial registry maintained by the National Library of Medicine. NCT01195883 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.