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NCT01190644 · ClinicalTrials.gov registry record · Phase 2

Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors

A Phase 2 study, sponsored by Merck Sharp & Dohme.

Terminated
Registry status
Phase 2
Development phase
5
Enrollment target

NCT01190644 is a Phase 2 study that was terminated before completion, run by Merck Sharp & Dohme. The registered enrollment target is 5 participants.

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The verdict

NCT01190644, a Phase 2 study, was terminated before completion, sponsored by Merck Sharp & Dohme.

TERMINATED
Registry status
Phase 2
Development phase
5 participants
Enrollment target

Study Summary

What hematopoietic precursor compartments as well as hemoglobin subtypes are affected by dosing with sotatercept (ACE-011)? Based upon a similar prior study with Procrit, Celgene has determined that all of these goals could be obtained by an intense 10-patient sotatercept (ACE-011) pharmacodynamic study, completed by two well-known experts in the red cell production field.

Interventions

  • DRUG Sotatercept

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2010-06-01
Est. Completion 2012-10-29
Phase Phase 2

Sponsor

Merck Sharp & Dohme

558 total trials

What the Registry Record Tells You About NCT01190644

The ClinicalTrials.gov registry entry for NCT01190644 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Sotatercept is the first listed.

NCT01190644 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01190644 about?

NCT01190644 is a clinical study titled "Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors". What hematopoietic precursor compartments as well as hemoglobin subtypes are affected by dosing with sotatercept (ACE-011)? Based upon a similar prior study with Procrit, Celgene has determined that all of these goals could be obtained by an intense 10-patient sotatercept (ACE-011) pharmacodynamic s...

What is the current status of trial NCT01190644?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2010-06-01. Estimated completion is 2012-10-29.

What interventions are being tested in trial NCT01190644?

The interventions under investigation include: Sotatercept (DRUG).

Who is sponsoring clinical trial NCT01190644?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.