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NCT01189643 · ClinicalTrials.gov registry record · Early Phase 1

Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor

A Early Phase 1 study of Sarcoma and Desmoplastic Small Round Cell Tumor (DSRCT), sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Early Phase 1
Development phase
15
Enrollment target
1
Study location

NCT01189643 is a Early Phase 1 study of Sarcoma and Desmoplastic Small Round Cell Tumor (DSRCT) that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 15 participants, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01189643, a Early Phase 1 study of Sarcoma and Desmoplastic Small Round Cell Tumor (DSRCT), is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This study adds irinotecan, temozolomide and bevacizumab to the chemotherapy regimen currently used to treat Desmoplastic small round cell tumor (DSRCT). The investigators are doing this study to find out what effects, good and/or bad, the combination of irinotecan, temozolomide and bevacizumab has on the patient and the DSRCT cancer.

Interventions

  • DRUG irinotecan, temozolomide, and bevacizumab incorporated into an existing schedule of high dose alkylator

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2010-08
Est. Completion 2026-08
Phase Early Phase 1

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT01189643

The ClinicalTrials.gov registry entry for NCT01189643 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (98% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Sarcoma appearing as the primary indexed condition, and to 1 intervention - of which irinotecan, temozolomide, and bevacizumab incorporated into an existing schedule of high dose alkylator is the first listed.

NCT01189643 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT01189643 about?

NCT01189643 is a clinical study titled "Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor". This study adds irinotecan, temozolomide and bevacizumab to the chemotherapy regimen currently used to treat Desmoplastic small round cell tumor (DSRCT). The investigators are doing this study to find out what effects, good and/or bad, the combination of irinotecan, temozolomide and bevacizumab has ...

What is the current status of trial NCT01189643?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2010-08. Estimated completion is 2026-08.

What conditions does trial NCT01189643 study?

This clinical trial studies the following conditions: Sarcoma, Desmoplastic Small Round Cell Tumor (DSRCT).

What interventions are being tested in trial NCT01189643?

The interventions under investigation include: irinotecan, temozolomide, and bevacizumab incorporated into an existing schedule of high dose alkylator (DRUG).

Who is sponsoring clinical trial NCT01189643?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01189643 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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