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NCT01189591 · ClinicalTrials.gov registry record · NA

Slow-wave Sleep Deprivation in Depression

A NA study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
NA
Development phase
25
Enrollment target

NCT01189591: Completed NA study, sponsored by University of Wisconsin, Madison.

NCT01189591 is a NA study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01189591, a NA study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
NA
Development phase
25 participants
Enrollment target

Study Summary

Sleep deprivation can acutely reverse depressive symptoms in patients with major depression. Although underlying mechanisms of the antidepressant action in sleep deprivation are unclear, many of these observations can be explained by abnormal slow wave homeostasis. This study will test the prediction that selectively reducing slow waves during sleep (slow wave deprivation; SWD), without disrupting total sleep time, will yield an antidepressant effect.

Interventions

  • DEVICE Slow-wave deprivation

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2009-06
Est. Completion 2011-08
Phase NA
University of Wisconsin, Madison

1,039 total trials

What the finished NCT01189591 record still lists

NCT01189591 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Slow-wave deprivation is the first listed.

NCT01189591 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01189591 about?

NCT01189591 is a clinical study titled "Slow-wave Sleep Deprivation in Depression". Sleep deprivation can acutely reverse depressive symptoms in patients with major depression. Although underlying mechanisms of the antidepressant action in sleep deprivation are unclear, many of these observations can be explained by abnormal slow wave homeostasis. This study will test the predictio...

What is the current status of trial NCT01189591?

This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2009-06. Estimated completion is 2011-08.

What interventions are being tested in trial NCT01189591?

The interventions under investigation include: Slow-wave deprivation (DEVICE).

Who is sponsoring clinical trial NCT01189591?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01189591's enrollment target sits among peer trials

25 1712th of 2000 higher than 265 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01189591, the US trial registry maintained by the National Library of Medicine. NCT01189591 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.