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NCT01185587 · ClinicalTrials.gov registry record
Sodium Channel Splicing in Heart Failure Trial
A clinical trial, sponsored by University of Illinois at Chicago.
- Completed
- Registry status
- 147
- Enrollment target
NCT01185587 is a clinical trial that has completed, run by University of Illinois at Chicago. The registered enrollment target is 147 participants.
The verdict
NCT01185587 has completed, sponsored by University of Illinois at Chicago.
- COMPLETED
- Registry status
- 147 participants
- Enrollment target
Study Summary
The purpose of this research is to see if investigators can detect truncated mRNA splice variants of the cardiac voltage-gated sodium (Na+) channel gene, SCN5A, in patients with a weak heart (Heart Failure) with or without an implantable cardioverter-defibrillator (ICD) and compare them to patients with a normal heart. Hypothesis: 1. Patients with reduced left ventricular ejection fraction have increased abundances truncated mRNA splice variants of the SCN5A gene, which portends to sodium channel dysfunction and an increased risk for sudden cardiac death. 2. Patients with implantable cardioverter-defibrillator devices (ICDs) who have experienced shock therapy have increased abundances of truncated mRNA splice variants of the SCN5A gene compared to similar congestive heart failure patients who have not experienced shock therapy.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 147 participants |
| Start Date | 2010-02 |
| Est. Completion | 2014-04 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01185587
The ClinicalTrials.gov registry entry for NCT01185587 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 147 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01185587 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01185587 about?
NCT01185587 is a clinical study titled "Sodium Channel Splicing in Heart Failure Trial". The purpose of this research is to see if investigators can detect truncated mRNA splice variants of the cardiac voltage-gated sodium (Na+) channel gene, SCN5A, in patients with a weak heart (Heart Failure) with or without an implantable cardioverter-defibrillator (ICD) and compare them to patients ...
What is the current status of trial NCT01185587?
This trial is currently completed. The enrollment target is 147 participants. The study started on 2010-02. Estimated completion is 2014-04.
Who is sponsoring clinical trial NCT01185587?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
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