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NCT01170962 · ClinicalTrials.gov registry record · Phase 2

Study of the Anti-HCV Drug (BMS-790052) Combined With Peginterferon and Ribavirin in Patients Who Failed Prior Treatment

A Phase 2 study of Hepatitis C Virus, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 2
Development phase
512
Enrollment target
20
Study locations

NCT01170962: Completed Phase 2 study of Hepatitis C Virus, sponsored by Bristol-Myers Squibb.

NCT01170962 is a Phase 2 study of Hepatitis C Virus that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 512 participants, above the 147-participant average among 3 other Hepatitis C Virus trials with a reported enrollment target (248% higher). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01170962, a Phase 2 study of Hepatitis C Virus, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 2
Development phase
512 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to determine whether BMS-790052 added to Peginterferon Alfa-2a and ribavirin can result in higher cure rates in patients who previously failed therapy and may have limited response to retreatment with Peginterferon Alfa-2a and ribavirin alone.

Primary Outcome

eRVR was defined as undetectable Hepatitis C virus RNA at both Weeks 4 and 12. HCV RNA levels were measured by the Roche COBAS® TaqMan® HCV Test version 2.0 from the central laboratory.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG BMS-790052
  • DRUG peginterferon alfa-2a
  • DRUG ribavirin

Study Locations (20)

California

  • Scripps Clinic - La Jolla
  • CLI - Los Angeles
  • Desta Digestive Disease Medical Center - San Diego
  • University Of California At San Francisco - San Francisco
  • California Pacific Medical Center - San Francisco
  • Kaiser Permanente Medical Center - San Francisco

Maryland

  • Mercy Medical Center - Baltimore
  • Digestive Disease Associates, P.A. - Baltimore
  • Johns Hopkins Medical Institutions - Lutherville

Florida

  • University Of Florida Hepatology - Gainesville
  • Miami Research Associates - South Miami

New York

  • Samuel S. Stratton Vamc - Albany
  • James Sungsik Park, M.D. C.N.S.C. - Great Neck

Alabama

  • Alabama Liver & Digestive Specialists (Alds) - Montgomery

Colorado

  • Transplant Center And Hepatology Clinic, B-154 - Aurora

Connecticut

  • Yale University School Of Medicine - New Haven

Indiana

  • Indiana University - Indianapolis

Trial Details

FieldValue
Enrollment Target 512 participants
Start Date 2010-08
Est. Completion 2012-12
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

What the finished NCT01170962 record still lists

NCT01170962 is an interventional study that assigns participants to a tested intervention. The registered 512 participants enrollment target is mid-sized for trials with a published cap, above the 147-participant average among 3 other Hepatitis C Virus trials with a reported enrollment target (248% higher).

The record links to 1 condition, with Hepatitis C Virus appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT01170962 names 20 study sites across 11 states, led by California, Maryland, Florida.

Frequently Asked Questions

What is clinical trial NCT01170962 about?

NCT01170962 is a clinical study titled "Study of the Anti-HCV Drug (BMS-790052) Combined With Peginterferon and Ribavirin in Patients Who Failed Prior Treatment". The purpose of this study is to determine whether BMS-790052 added to Peginterferon Alfa-2a and ribavirin can result in higher cure rates in patients who previously failed therapy and may have limited response to retreatment with Peginterferon Alfa-2a and ribavirin alone.

What is the current status of trial NCT01170962?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 512 participants. The study started on 2010-08. Estimated completion is 2012-12.

What conditions does trial NCT01170962 study?

This clinical trial studies the following conditions: Hepatitis C Virus.

What interventions are being tested in trial NCT01170962?

The interventions under investigation include: Placebo (DRUG), BMS-790052 (DRUG), peginterferon alfa-2a (DRUG), ribavirin (DRUG).

Who is sponsoring clinical trial NCT01170962?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01170962 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT01170962, the US trial registry maintained by the National Library of Medicine. NCT01170962 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.