Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01163084 · ClinicalTrials.gov registry record · Phase 1

Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 1
Development phase
10
Enrollment target

NCT01163084: Clinical Trial Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT01163084 is a Phase 1 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01163084, a Phase 1 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

This randomized phase I/II trial studies giving leuprolide acetate or goserelin acetate together with or without vismodegib followed by surgery to see how well they work in treating patients with prostate cancer that has spread from where it started to nearby tissue or lymph nodes. Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide acetate or goserelin acetate, may lessen the amount of androgens made by the body. Vismodegib may slow the growth of tumor cells. Giving antihormone therapy together with vismodegib may be an effective treatment for prostate cancer.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Vismodegib
  • DRUG Goserelin Acetate
  • DRUG Leuprolide Acetate

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2010-07-09
Est. Completion 2012-06-01
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01163084

The ClinicalTrials.gov registry entry for NCT01163084 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT01163084 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01163084 about?

NCT01163084 is a clinical study titled "Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer". This randomized phase I/II trial studies giving leuprolide acetate or goserelin acetate together with or without vismodegib followed by surgery to see how well they work in treating patients with prostate cancer that has spread from where it started to nearby tissue or lymph nodes. Androgens can cau...

What is the current status of trial NCT01163084?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2010-07-09. Estimated completion is 2012-06-01.

What interventions are being tested in trial NCT01163084?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Vismodegib (DRUG), Goserelin Acetate (DRUG), Leuprolide Acetate (DRUG).

Who is sponsoring clinical trial NCT01163084?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.