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NCT01159574 · ClinicalTrials.gov registry record · Phase 2

Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma

A Phase 2 study, sponsored by Weill Medical College of Cornell University.

Completed
Registry status
Phase 2
Development phase
121
Enrollment target

NCT01159574: Completed Phase 2 study, sponsored by Weill Medical College of Cornell University.

NCT01159574 is a Phase 2 study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 121 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01159574, a Phase 2 study, has completed, sponsored by Weill Medical College of Cornell University.

COMPLETED
Registry status
Phase 2
Development phase
121 participants
Enrollment target

Study Summary

This study is intended to investigate the combination of the combination of dexamethasone (Decadron®), Clarithromycin (Biaxin®), and pomalidomide (CC-4047®) \[ClaPd\] in multiple myeloma patients who have relapsed or refractory disease who have failed prior treatment with lenalidomide when used alone or in combination with corticosteroids. Primary endpoint will be response rate to treatment. Secondary endpoints will include toxicity of the combination, time to maximum response, and time to disease progression

Primary Outcome

Best response rate was recorded for all patients, using the IMWG criteria.

Interventions

  • DRUG Pomalidomide
  • DRUG dexamethasone
  • DRUG clarithromycin

Trial Details

FieldValue
Enrollment Target 121 participants
Start Date 2010-08
Est. Completion 2015-05-05
Phase Phase 2

What the finished NCT01159574 record still lists

NCT01159574 is an interventional study that assigns participants to a tested intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.

The record links to 0 conditions, and to 3 interventions - of which Pomalidomide is the first listed.

NCT01159574 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01159574 about?

NCT01159574 is a clinical study titled "Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma". This study is intended to investigate the combination of the combination of dexamethasone (Decadron®), Clarithromycin (Biaxin®), and pomalidomide (CC-4047®) \[ClaPd\] in multiple myeloma patients who have relapsed or refractory disease who have failed prior treatment with lenalidomide when used alon...

What is the current status of trial NCT01159574?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 121 participants. The study started on 2010-08. Estimated completion is 2015-05-05.

What interventions are being tested in trial NCT01159574?

The interventions under investigation include: Pomalidomide (DRUG), dexamethasone (DRUG), clarithromycin (DRUG).

Who is sponsoring clinical trial NCT01159574?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01159574's enrollment target sits among peer trials

121 567th of 2000 higher than 1,432 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01159574, the US trial registry maintained by the National Library of Medicine. NCT01159574 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.