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NCT01156428 · ClinicalTrials.gov registry record
Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease
A clinical trial, sponsored by The Rogosin Institute.
- Completed
- Registry status
- 119
- Enrollment target
NCT01156428: Completed study, sponsored by The Rogosin Institute.
NCT01156428 is a clinical trial that has completed, run by The Rogosin Institute. The registered enrollment target is 119 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01156428 has completed, sponsored by The Rogosin Institute.
- COMPLETED
- Registry status
- 119 participants
- Enrollment target
Study Summary
This study will evaluate in patients with kidney disease, the role that certain inflammatory and immune mediators play in promoting kidney damage. The investigators hypothesize that certain mediators, (identified in the serum, urine and renal biopsy tissue), of patients with a variety of different renal disease states will provide information regarding their clinical course and that inflammatory and immune patterns in the serum and urine of patients with kidney disease may yield predictive diagnostic information in place of a renal biopsy. The ability to detect and quantify these mediators may lead to earlier detection and treatment of kidney disease in order to prevent kidney failure and the requirement for renal replacement. The study will evaluate serum, blood and urine collected over a one year period post kidney biopsy for the presence of inflammatory or immune mediators, which will be correlated with kidney pathology findings (gene signatures). These gene signatures will be compared to "normal" control specimens obtained from donor transplant kidneys or from normal kidney tissue obtained from patients who require their entire kidney removed for a tumor.
Primary Outcome
To determine the deviation from the norm of blood and urine inflammatory and immune mediators in subjects that have undergone renal biopsy for clinical indication with resultant biopsy diagnosed renal conditions. To determine the correlation of serum, whole blood and urine inflammatory and immune mediators with the renal pathologic diagnosis as well as the gene signature of the given pathology.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2010-07 |
| Est. Completion | 2016-11 |
What the finished NCT01156428 record still lists
NCT01156428 is an observational study that tracks outcomes without assigning an intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01156428 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01156428 about?
NCT01156428 is a clinical study titled "Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease". This study will evaluate in patients with kidney disease, the role that certain inflammatory and immune mediators play in promoting kidney damage. The investigators hypothesize that certain mediators, (identified in the serum, urine and renal biopsy tissue), of patients with a variety of different r...
What is the current status of trial NCT01156428?
This trial is currently completed. The enrollment target is 119 participants. The study started on 2010-07. Estimated completion is 2016-11.
Who is sponsoring clinical trial NCT01156428?
This trial is sponsored by The Rogosin Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.
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