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NCT01149863 · ClinicalTrials.gov registry record · Phase 2

Alteration in Timing of Plerixafor Administration

A Phase 2 study, sponsored by Emory University.

Completed
Registry status
Phase 2
Development phase
34
Enrollment target

NCT01149863: Completed Phase 2 study, sponsored by Emory University.

NCT01149863 is a Phase 2 study that has completed, run by Emory University. The registered enrollment target is 34 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01149863, a Phase 2 study, has completed, sponsored by Emory University.

COMPLETED
Registry status
Phase 2
Development phase
34 participants
Enrollment target

Study Summary

Typically, the collection of blood cells for autologous stem cell transplant is done after the drugs granulocyte colony-stimulating factor (G-CSF) and plerixafor have been given to activate the bone marrow stem cells to produce a certain type of blood cell, called CD34+ cells. Currently, plerixafor is given in the evening, about 11 hours before apheresis (removal of blood) begins the following morning. The purpose of this study is to test whether plerixafor can instead be given 17 hours before apheresis. This timing would be more convenient since plerixafor would be given during normal clinic hours, and so patients would be within a clinic environment if any side effects develop. The study will look for the activation of CD34+ cells in patients who receive plerixafor 17 hours before apheresis. We will follow the number of patients that achieve the target numbers of CD34+ cells, and the total number of CD34+ cells collected. These will be compared to the numbers in previous studies giving plerixafor 11 hours before apheresis. We will also assess the safety of giving plerixafor 17 hours before apheresis.

Interventions

  • DRUG Plerixafor

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2010-06
Phase Phase 2
Emory University

1,208 total trials

What the finished NCT01149863 record still lists

NCT01149863 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower).

The record links to 0 conditions, and to 1 intervention - of which Plerixafor is the first listed.

NCT01149863 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01149863 about?

NCT01149863 is a clinical study titled "Alteration in Timing of Plerixafor Administration". Typically, the collection of blood cells for autologous stem cell transplant is done after the drugs granulocyte colony-stimulating factor (G-CSF) and plerixafor have been given to activate the bone marrow stem cells to produce a certain type of blood cell, called CD34+ cells. Currently, plerixafor ...

What is the current status of trial NCT01149863?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2010-06.

What interventions are being tested in trial NCT01149863?

The interventions under investigation include: Plerixafor (DRUG).

Who is sponsoring clinical trial NCT01149863?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01149863's enrollment target sits among peer trials

34 1539th of 2000 higher than 448 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01149863, the US trial registry maintained by the National Library of Medicine. NCT01149863 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.