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NCT01149616 · ClinicalTrials.gov registry record · Phase 4
Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
A Phase 4 study, sponsored by Beth Israel Deaconess Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 82
- Enrollment target
NCT01149616: Clinical Trial Phase 4 study, sponsored by Beth Israel Deaconess Medical Center.
NCT01149616 is a Phase 4 study that was terminated before completion, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 82 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01149616, a Phase 4 study, was terminated before completion, sponsored by Beth Israel Deaconess Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 82 participants
- Enrollment target
Study Summary
The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects. However, the analgesic effects of dexamethasone have not been adequately researched. Following surgery, patients are typically discharged home with PO opiates to manage post-operative pain. The investigators believe that by using VAS (Visual Analog Scale) for Pain the investigators can show that a single dose of dexamethasone can reduce pain scales and opiate consumption post-operatively, on Post Operative Day (POD 1) when compared to placebo.
Primary Outcome
Patients were instructed to select a number between zero and ten to indicate the degree of pain they experience (zero being no pain and ten being the worst pain they could imagine). Therefore, ten is worse than zero.
Interventions
- DRUG placebo
- DRUG Dexamethasone 8mg iv x1
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2009-12 |
| Est. Completion | 2012-12 |
| Phase | Phase 4 |
Why NCT01149616 stopped before completion
NCT01149616 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (84% lower).
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT01149616 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01149616 about?
NCT01149616 is a clinical study titled "Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery". The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects. However, the analgesic effects of dexamethasone have not been adequately researched. Follo...
What is the current status of trial NCT01149616?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 82 participants. The study started on 2009-12. Estimated completion is 2012-12.
What interventions are being tested in trial NCT01149616?
The interventions under investigation include: placebo (DRUG), Dexamethasone 8mg iv x1 (DRUG).
Who is sponsoring clinical trial NCT01149616?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01149616's enrollment target sits among peer trials
82 939th of 2000 higher than 1,061 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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