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NCT01148849 · ClinicalTrials.gov registry record · Phase 1

Safety Study of MGAH22 in HER2-positive Carcinomas

A Phase 1 study, sponsored by MacroGenics.

Completed
Registry status
Phase 1
Development phase
66
Enrollment target

NCT01148849 is a Phase 1 study that has completed, run by MacroGenics. The registered enrollment target is 66 participants.

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The verdict

NCT01148849, a Phase 1 study, has completed, sponsored by MacroGenics.

COMPLETED
Registry status
Phase 1
Development phase
66 participants
Enrollment target

Study Summary

The purpose of this study is to determine if MGAH22 is safe when given by intravenous (IV) infusion to patients with HER2-positive cancer. The study will also evaluate how long MGAH22 stays in the blood and how long it takes for it to leave the body, what is the highest dose that can safely be given, and whether it has an effect on tumors.

Interventions

  • BIOLOGICAL margetuximab

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2010-07
Est. Completion 2022-06-14
Phase Phase 1

Sponsor

MacroGenics

36 total trials

What the Registry Record Tells You About NCT01148849

The ClinicalTrials.gov registry entry for NCT01148849 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MacroGenics, which has 36 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which margetuximab is the first listed.

NCT01148849 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01148849 about?

NCT01148849 is a clinical study titled "Safety Study of MGAH22 in HER2-positive Carcinomas". The purpose of this study is to determine if MGAH22 is safe when given by intravenous (IV) infusion to patients with HER2-positive cancer. The study will also evaluate how long MGAH22 stays in the blood and how long it takes for it to leave the body, what is the highest dose that can safely be given...

What is the current status of trial NCT01148849?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2010-07. Estimated completion is 2022-06-14.

What interventions are being tested in trial NCT01148849?

The interventions under investigation include: margetuximab (BIOLOGICAL).

Who is sponsoring clinical trial NCT01148849?

This trial is sponsored by MacroGenics, which has 36 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.