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NCT01147861 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study to Evaluate the Effect of GSK256073, an HM74A Receptor Agonist, on Glucose and NEFA Levels in Type 2 Diabetics

A Phase 1 study, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 1
Development phase
39
Enrollment target

NCT01147861 is a Phase 1 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 39 participants.

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The verdict

NCT01147861, a Phase 1 study, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 1
Development phase
39 participants
Enrollment target

Study Summary

The aim of this study is to verify whether a significant decrease in glucose levels can be achieved with the HM74A agonist GSK256073 in type 2 diabetic patients. Several dose levels and a placebo will be evaluated in a three period crossover study with two active doses and one placebo dose per subject, in order to determine whether there is a dose that produces glucose lowering in the target population. In addition, this study will investigate the optimal dosing regimen for full manifestation of any metabolic effect of GSK256073 by comparing once a day versus twice a day regimens.

Interventions

  • OTHER Placebo
  • DRUG GSK256073

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2010-07-01
Est. Completion 2010-09-07
Phase Phase 1

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT01147861

The ClinicalTrials.gov registry entry for NCT01147861 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 39 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01147861 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01147861 about?

NCT01147861 is a clinical study titled "A Phase 1 Study to Evaluate the Effect of GSK256073, an HM74A Receptor Agonist, on Glucose and NEFA Levels in Type 2 Diabetics". The aim of this study is to verify whether a significant decrease in glucose levels can be achieved with the HM74A agonist GSK256073 in type 2 diabetic patients. Several dose levels and a placebo will be evaluated in a three period crossover study with two active doses and one placebo dose per subje...

What is the current status of trial NCT01147861?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 2010-07-01. Estimated completion is 2010-09-07.

What interventions are being tested in trial NCT01147861?

The interventions under investigation include: Placebo (OTHER), GSK256073 (DRUG).

Who is sponsoring clinical trial NCT01147861?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.