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NCT01143792 · ClinicalTrials.gov registry record · Phase 2

Evaluation of Treatments for Homeless Youths

A Phase 2 study of Substance Abuse, sponsored by Ohio State University.

Completed
Registry status
Phase 2
Development phase
270
Enrollment target
1
Study location

NCT01143792 is a Phase 2 study of Substance Abuse that has completed, run by Ohio State University. The registered enrollment target is 270 participants, below the 5,255-participant average among 58 other Substance Abuse trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01143792, a Phase 2 study of Substance Abuse, has completed, sponsored by Ohio State University.

COMPLETED
Registry status
Phase 2
Development phase
270 participants
Enrollment target
1
Study location

Study Summary

Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population. Studies document high rates of substance use, HIV risk, mental health problems, teenage pregnancy and criminality. Research to date examining homeless, street living youth has been primarily descriptive; less effort has been directed towards developing and evaluating treatment interventions for this group. The majority of homeless youth do not receive substance abuse treatment, with one study reporting that only 15% of street living youth report ever receiving mental health services. The effectiveness of the Community Reinforcement Approach (CRA) with street living youth was studied in our recently completed Stage 1 trial. The proposed study is a Stage II clinical trial examining outcome of CRA individual therapy as compared to two interventions commonly employed, yet little researched, with this group. All clients will be randomized to one of three theoretically distinct interventions: (1) CRA therapy, (2) Motivational Enhancement Therapy (MET), or (3) Case Management (CM). The relative effectiveness of these interventions will be evaluated at 3, 6, and 12 months post-baseline. The Social Ecology Theory of Development (Bronfenbrenner, 1979) guides our change hypotheses and intervention. Proposed change mechanisms (mediators) for each intervention will be evaluated. Differential treatment response as a function of ethnicity, gender, age, sexual orientation and abuse (moderators) will be investigated to better understand the interventions. The study will also examine how, if at all, treatment engagement, retention and expectations impact youth response to the three treatments. Information gained through this project may help address the gap in our understanding of how best to effectively intervene with a group at high risk for continuing health and psychological problems.

Conditions Studied

Interventions

  • BEHAVIORAL Community Reinforcement Approach (CRA) + HIV prevention
  • BEHAVIORAL Case Management + HIV Prevention
  • BEHAVIORAL Motivational Enhancement Therapy (MET) + HIV prevention

Study Locations (1)

Ohio

  • The Ohio State University - Columbus

Trial Details

FieldValue
Enrollment Target 270 participants
Start Date 2006-09
Est. Completion 2012-06
Phase Phase 2

Sponsor

Ohio State University

552 total trials

What the Registry Record Tells You About NCT01143792

The ClinicalTrials.gov registry entry for NCT01143792 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 270 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,255-participant average among 58 other Substance Abuse trials with a reported enrollment target (95% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Substance Abuse appearing as the primary indexed condition, and to 3 interventions - of which Community Reinforcement Approach (CRA) + HIV prevention is the first listed.

NCT01143792 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT01143792 about?

NCT01143792 is a clinical study titled "Evaluation of Treatments for Homeless Youths". Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population. Studies document high rates of substance use, HIV risk, mental health problems, teenage pregnancy and crimin...

What is the current status of trial NCT01143792?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 270 participants. The study started on 2006-09. Estimated completion is 2012-06.

What conditions does trial NCT01143792 study?

This clinical trial studies the following conditions: Substance Abuse.

What interventions are being tested in trial NCT01143792?

The interventions under investigation include: Community Reinforcement Approach (CRA) + HIV prevention (BEHAVIORAL), Case Management + HIV Prevention (BEHAVIORAL), Motivational Enhancement Therapy (MET) + HIV prevention (BEHAVIORAL).

Who is sponsoring clinical trial NCT01143792?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01143792 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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