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NCT01140152 · ClinicalTrials.gov registry record

Proteomic Analysis Reveals Innate Immune Activity In Intestinal Transplant Dysfunction

A clinical trial, sponsored by University of California, Los Angeles.

Completed
Registry status
17
Enrollment target

NCT01140152: Completed study, sponsored by University of California, Los Angeles.

NCT01140152 is a clinical trial that has completed, run by University of California, Los Angeles. The registered enrollment target is 17 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01140152 has completed, sponsored by University of California, Los Angeles.

COMPLETED
Registry status
17 participants
Enrollment target

Study Summary

Many patients with intestinal failure require intestinal transplantation for survival. Currently, the gold standard for diagnosing acute cellular rejection (ACR) is histological examination of endoscopic biopsies, which are taken invasively and lack sensitivity. A non-invasive method of monitoring for ACR is needed.

Primary Outcome

Protocol biopsies of the transplanted intestine are obtained during endoscopy and when clinical symptoms indicating abnormal allograft function are present. Biopsies were sent to pathology, where the pathologist determined if there was acute rejection. Ostomy effluent taken during times of endoscopy were subjected to MALDI and Luminex technology to look for any proteins or cytokines differentially expressed during rejection.

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2008-07
Est. Completion 2009-09

What the finished NCT01140152 record still lists

NCT01140152 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 17 participants, a relatively small participant target.

The record links to 0 conditions, and to 0 interventions.

NCT01140152 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01140152 about?

NCT01140152 is a clinical study titled "Proteomic Analysis Reveals Innate Immune Activity In Intestinal Transplant Dysfunction". Many patients with intestinal failure require intestinal transplantation for survival. Currently, the gold standard for diagnosing acute cellular rejection (ACR) is histological examination of endoscopic biopsies, which are taken invasively and lack sensitivity. A non-invasive method of monitoring f...

What is the current status of trial NCT01140152?

This trial is currently completed. The enrollment target is 17 participants. The study started on 2008-07. Estimated completion is 2009-09.

Who is sponsoring clinical trial NCT01140152?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT01140152, the US trial registry maintained by the National Library of Medicine. NCT01140152 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.