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NCT01135394 · ClinicalTrials.gov registry record · NA

Pharmacogenomics of Thiazolidinediones

A NA study, sponsored by University of Maryland, Baltimore.

Completed
Registry status
NA
Development phase
114
Enrollment target

NCT01135394: Completed NA study, sponsored by University of Maryland, Baltimore.

NCT01135394 is a NA study that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 114 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01135394, a NA study, has completed, sponsored by University of Maryland, Baltimore.

COMPLETED
Registry status
NA
Development phase
114 participants
Enrollment target

Study Summary

The purpose of this study is to determine predictors of response to pioglitazone, an anti-diabetic medication. The investigators know from randomized clinical trials that some 30% of patients do not respond to this type of medication. There is presently no way to identify this group of patients leading to unnecessary drug exposure and medication costs.

Primary Outcome

Change in insulin resistance was calculated as change (end of treatment minus baseline) in HOMA-IR index (glucose (mg/dL) x insulin (μU/mL)/405)

Interventions

  • DRUG Pioglitazone

Trial Details

FieldValue
Enrollment Target 114 participants
Start Date 2009-03
Est. Completion 2018-05-31
Phase NA
University of Maryland, Baltimore

560 total trials

What the finished NCT01135394 record still lists

NCT01135394 is an interventional study that assigns participants to a tested intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Pioglitazone is the first listed.

NCT01135394 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01135394 about?

NCT01135394 is a clinical study titled "Pharmacogenomics of Thiazolidinediones". The purpose of this study is to determine predictors of response to pioglitazone, an anti-diabetic medication. The investigators know from randomized clinical trials that some 30% of patients do not respond to this type of medication. There is presently no way to identify this group of patients lead...

What is the current status of trial NCT01135394?

This trial is currently completed. It is a NA study. The enrollment target is 114 participants. The study started on 2009-03. Estimated completion is 2018-05-31.

What interventions are being tested in trial NCT01135394?

The interventions under investigation include: Pioglitazone (DRUG).

Who is sponsoring clinical trial NCT01135394?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01135394's enrollment target sits among peer trials

114 811th of 2000 higher than 1,188 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01135394, the US trial registry maintained by the National Library of Medicine. NCT01135394 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.