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NCT01135277 · ClinicalTrials.gov registry record
Immune Suppression and Ventilator Associated Pneumonias
A clinical trial of Sepsis, sponsored by Matthew Exline.
- Completed
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT01135277: Completed study of Sepsis, sponsored by Matthew Exline.
NCT01135277 is a study of Sepsis that has completed, run by Matthew Exline. The registered enrollment target is 50 participants, below the 6,564-participant average among 90 other Sepsis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01135277, a study of Sepsis, has completed, sponsored by Matthew Exline.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients in the ICU are already predisposed to nosocomial infections, which are both costly and potentially life threatening, and it appears that the immune paralysis of sepsis may put these patients at greater risk for secondary infections, though this has not been proven conclusively. One measure of this sepsis-induced immune suppression is monocyte deactivation. The investigators hypothesize that, as a cornerstone of the monocytic innate immune response to infection, the inflammasome is critical to monocyte function during sepsis.
Primary Outcome
Blood and BAL fluid will be collected at Day 1
Conditions Studied
Study Locations (1)
Ohio
- The Ohio State University - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2010-02 |
| Est. Completion | 2012-11 |
What the finished NCT01135277 record still lists
NCT01135277 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 6,564-participant average among 90 other Sepsis trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Sepsis appearing as the primary indexed condition, and to 0 interventions.
NCT01135277 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT01135277 about?
NCT01135277 is a clinical study titled "Immune Suppression and Ventilator Associated Pneumonias". Patients in the ICU are already predisposed to nosocomial infections, which are both costly and potentially life threatening, and it appears that the immune paralysis of sepsis may put these patients at greater risk for secondary infections, though this has not been proven conclusively. One measure ...
What is the current status of trial NCT01135277?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2010-02. Estimated completion is 2012-11.
What conditions does trial NCT01135277 study?
This clinical trial studies the following conditions: Sepsis.
Who is sponsoring clinical trial NCT01135277?
This trial is sponsored by Matthew Exline, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01135277 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01135277's enrollment target sits among peer trials
50 72nd of 90 higher than 16 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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