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NCT01132885 · ClinicalTrials.gov registry record

Defining the Brain Phenotype of Children With Williams Syndrome

A clinical trial of Williams Syndrome and Duplication, sponsored by National Institute of Mental Health (NIMH).

Recruiting
Registry status
415
Enrollment target
1
Study location

NCT01132885 is a study of Williams Syndrome and Duplication that is actively recruiting participants, run by National Institute of Mental Health (NIMH). The registered enrollment target is 415 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01132885, a study of Williams Syndrome and Duplication, is actively recruiting participants, sponsored by National Institute of Mental Health (NIMH).

RECRUITING
Registry status
415 participants
Enrollment target
1
Study location

Study Summary

Background: \- Little is known about how the brain changes during childhood and adolescence, how genes affect this process, or how the brains of people with 7q11.23 genetic variation change during this period. Researchers are interested in using magnetic resonance imaging to study how the brain changes in healthy children and children with 7q11.23 genetic variation, including Williams syndrome and 7q11.23 duplication syndrome. Objectives: \- To study developmental changes in the brains of healthy children and children who have been diagnosed with Williams syndrome,7q11.23 duplication syndrome, or other 7q11.23 genetic variation. Eligibility: * Healthy children and adolescents between 5 and 17 years of age. * Children and adolescents between 5 and 17 years of age who have been diagnosed with Williams syndrome, 7q11.23 duplication syndrome, or have other 7q11.23 genetic variation. Design: * Participants will have a brief physical examination and tests of memory, attention, concentration, and thinking. Parents will be asked about their child s personality, behavior characteristics, and social interaction and communication skills. * Both participants and their parents may be asked to complete additional questionnaires or take various tests as required for the study. * Participants will have approximately 10 hours of magnetic resonance imaging (MRI) scanning, usually over 4 to 5 days, within a one month period. Some of these tests will require the participants to do specific tasks while inside the MRI scanner. * Participants will be asked to return to the National Institutes of Health clinical center to repeat these procedures every 2 years thereafter until age 18.

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 415 participants
Start Date 2011-01-23

What the Registry Record Tells You About NCT01132885

The ClinicalTrials.gov registry entry for NCT01132885 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 415 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Williams Syndrome appearing as the primary indexed condition, and to 0 interventions.

NCT01132885 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT01132885 about?

NCT01132885 is a clinical study titled "Defining the Brain Phenotype of Children With Williams Syndrome". Background: \- Little is known about how the brain changes during childhood and adolescence, how genes affect this process, or how the brains of people with 7q11.23 genetic variation change during this period. Researchers are interested in using magnetic resonance imaging to study how the brain cha...

What is the current status of trial NCT01132885?

This trial is currently recruiting. The enrollment target is 415 participants. The study started on 2011-01-23.

What conditions does trial NCT01132885 study?

This clinical trial studies the following conditions: Williams Syndrome, Duplication.

Who is sponsoring clinical trial NCT01132885?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01132885 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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