Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01128361 · ClinicalTrials.gov registry record · NA
Pilot Study of Aerobic Exercise in Early Alzheimer's Disease(AD)
A NA study, sponsored by Jeff Burns, MD.
- Completed
- Registry status
- NA
- Development phase
- 76
- Enrollment target
NCT01128361: Completed NA study, sponsored by Jeff Burns, MD.
NCT01128361 is a NA study that has completed, run by Jeff Burns, MD. The registered enrollment target is 76 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01128361, a NA study, has completed, sponsored by Jeff Burns, MD.
- COMPLETED
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
Study Summary
The current project is a natural extension of a programmatic line of investigation into the relationship between exercise, brain aging, and AD that Dr. Burns has developed over the last four years. The current study will provide data to estimate expected effect sizes for power analyses and sample size calculations. It will also provide an opportunity to optimally design a larger trial that can be extended to multiple sites to more definitively examine the role of exercise as a therapy in AD. The current project's aims are an important and necessary developmental step given the lack of fitness data in AD and the limited knowledge of the mechanisms that may form the basis of an association between aerobic fitness and AD.
Primary Outcome
A composite measure of several memory tests (Logical Memory (Immediate and Delayed), Free and Cued Selective Reminding Test (sum of free recall). Each score was normalized to an independent dataset of individuals without dementia. Then the 4 standardized scores were averaged. Numbers closer to positive indicate better memory performance. The scores are centered around a mean of 0 and standardized so each value represents a fraction of the standard deviation. There are no limits to the scores.
Interventions
- BEHAVIORAL Aerobic Exercise
- BEHAVIORAL Stretching
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2010-05 |
| Est. Completion | 2015-04 |
| Phase | NA |
What the finished NCT01128361 record still lists
NCT01128361 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Aerobic Exercise is the first listed.
NCT01128361 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01128361 about?
NCT01128361 is a clinical study titled "Pilot Study of Aerobic Exercise in Early Alzheimer's Disease(AD)". The current project is a natural extension of a programmatic line of investigation into the relationship between exercise, brain aging, and AD that Dr. Burns has developed over the last four years. The current study will provide data to estimate expected effect sizes for power analyses and sample si...
What is the current status of trial NCT01128361?
This trial is currently completed. It is a NA study. The enrollment target is 76 participants. The study started on 2010-05. Estimated completion is 2015-04.
What interventions are being tested in trial NCT01128361?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL), Stretching (BEHAVIORAL).
Who is sponsoring clinical trial NCT01128361?
This trial is sponsored by Jeff Burns, MD, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01128361's enrollment target sits among peer trials
76 1062nd of 2000 higher than 932 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02615184 · 76 participants · Phase 2
A Study to Check the Safety of Dexlansoprazole and Learn If it Can Heal Erosive Esophagitis (EE) and Keep it Healed in Children 2 to 11 Years Old
- NCT02821741 · 76 participants · NA
Effects of External Ear Stimulation on Pain Perception and Mood
- NCT03019757 · 76 participants
Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
- NCT03353584 · 76 participants · NA
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia