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NCT01123005 · ClinicalTrials.gov registry record · Phase 1

Imaging and Biomarkers of Hypoxia in Solid Tumors

A Phase 1 study, sponsored by Stanford University.

Terminated
Registry status
Phase 1
Development phase
28
Enrollment target

NCT01123005: Clinical Trial Phase 1 study, sponsored by Stanford University.

NCT01123005 is a Phase 1 study that was terminated before completion, run by Stanford University. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01123005, a Phase 1 study, was terminated before completion, sponsored by Stanford University.

TERMINATED
Registry status
Phase 1
Development phase
28 participants
Enrollment target

Study Summary

Hypoxia, meaning a lack of oxygen, has been associated strongly with a wide range of human cancers. Hypoxia occurs when tumor growth exceeds the ability of blood vessels to supply the tumor with oxygenated blood. It is currently understood that hypoxic tumors are more aggressive. Current methods for measuring hypoxia include invasive procedures such as tissue biopsy, or insertion of an electrode into the tumor. EF5-PET may be a non-invasive way to measure tumor hypoxia.

Interventions

  • DRUG Dichloroacetate
  • DRUG EF5
  • PROCEDURE PET Scan
  • DRUG Carbogen

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2010-12
Est. Completion 2015-08-21
Phase Phase 1
Stanford University

1,744 total trials

Why NCT01123005 stopped before completion

NCT01123005 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).

The record links to 0 conditions, and to 4 interventions - of which Dichloroacetate is the first listed.

NCT01123005 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01123005 about?

NCT01123005 is a clinical study titled "Imaging and Biomarkers of Hypoxia in Solid Tumors". Hypoxia, meaning a lack of oxygen, has been associated strongly with a wide range of human cancers. Hypoxia occurs when tumor growth exceeds the ability of blood vessels to supply the tumor with oxygenated blood. It is currently understood that hypoxic tumors are more aggressive. Current methods for...

What is the current status of trial NCT01123005?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2010-12. Estimated completion is 2015-08-21.

What interventions are being tested in trial NCT01123005?

The interventions under investigation include: Dichloroacetate (DRUG), EF5 (DRUG), PET Scan (PROCEDURE), Carbogen (DRUG).

Who is sponsoring clinical trial NCT01123005?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01123005's enrollment target sits among peer trials

28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01123005, the US trial registry maintained by the National Library of Medicine. NCT01123005 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.