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NCT01113684 · ClinicalTrials.gov registry record
Study of Subthalamic Brain Stimulation in Parkinson Disease (PD)
A clinical trial, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- 175
- Enrollment target
NCT01113684: Completed study, sponsored by University of Alabama at Birmingham.
NCT01113684 is a clinical trial that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 175 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01113684 has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- 175 participants
- Enrollment target
Study Summary
Deep brain stimulation (DBS) improves debilitating symptoms of movement disorders when conventional medical therapies and novel surgical therapies fail. Despite the remarkable efficacy of DBS, its therapeutic mechanism remains unclear. There is controversy regarding whether the therapeutic effects of DBS are associated with inhibition or excitation of target neurons, the introduction of new activity into the network, or a combination of these mechanisms. Additionally, it is unclear why stimulus frequency plays an important role in the clinical response to therapy. The fundamental hypothesis of this proposal is that unilateral subthalamic nucleus (STN) DBS in PD alters neuronal activity in the bilateral basal ganglia-thalamic-cortical motor system in a manner that is dependent on stimulation frequency.
Interventions
- DEVICE Implantable pulse generator (deep brain stimulator)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 175 participants |
| Start Date | 2010-02 |
| Est. Completion | 2014-11 |
What the finished NCT01113684 record still lists
NCT01113684 is an observational study that tracks outcomes without assigning an intervention. The registered 175 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Implantable pulse generator (deep brain stimulator) is the first listed.
NCT01113684 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01113684 about?
NCT01113684 is a clinical study titled "Study of Subthalamic Brain Stimulation in Parkinson Disease (PD)". Deep brain stimulation (DBS) improves debilitating symptoms of movement disorders when conventional medical therapies and novel surgical therapies fail. Despite the remarkable efficacy of DBS, its therapeutic mechanism remains unclear. There is controversy regarding whether the therapeutic effects o...
What is the current status of trial NCT01113684?
This trial is currently completed. The enrollment target is 175 participants. The study started on 2010-02. Estimated completion is 2014-11.
What interventions are being tested in trial NCT01113684?
The interventions under investigation include: Implantable pulse generator (deep brain stimulator) (DEVICE).
Who is sponsoring clinical trial NCT01113684?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
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