Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01101386 · ClinicalTrials.gov registry record
Study of Cyclodextrin (SBECD) and Voriconazole Blood Concentrations During Continuous Dialysis
A clinical trial of Fungal Infection, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 10
- Enrollment target
- 1
- Study location
NCT01101386: Completed study of Fungal Infection, sponsored by University of Colorado, Denver.
NCT01101386 is a study of Fungal Infection that has completed, run by University of Colorado, Denver. The registered enrollment target is 10 participants, below the 161-participant average among 6 other Fungal Infection trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01101386, a study of Fungal Infection, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
This study's primary objective is to determine if continuous renal replacement therapy (CRRT) can adequately remove the sulfobutylether-ß-cyclodextrin sodium (SBECD) vehicle from the blood so that intravenous voriconazole can be utilized in critically ill patients with renal dysfunction requiring dialysis. Secondarily, the pharmacokinetics of intravenous voriconazole and its metabolite (UK121-265) and adverse effects of SBECD accumulation will also be evaluated. The study hypothesis is that CRRT is effective at removing SBECD and allows patients to receive intravenous voriconazole without the concern of SBECD accumulation.
Primary Outcome
Evaluate SBECD pharmacokinetics (Cmax, Cmin, AUC, half-life, CL, seiving coefficient). Predict time to SBECD accumulation in study patients
Conditions Studied
Interventions
- DRUG Voriconazole
Study Locations (1)
Colorado
- University of Colorado Hospital - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2010-05 |
| Est. Completion | 2012-11 |
What the finished NCT01101386 record still lists
NCT01101386 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 161-participant average among 6 other Fungal Infection trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Fungal Infection appearing as the primary indexed condition, and to 1 intervention - of which Voriconazole is the first listed.
NCT01101386 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT01101386 about?
NCT01101386 is a clinical study titled "Study of Cyclodextrin (SBECD) and Voriconazole Blood Concentrations During Continuous Dialysis". This study's primary objective is to determine if continuous renal replacement therapy (CRRT) can adequately remove the sulfobutylether-ß-cyclodextrin sodium (SBECD) vehicle from the blood so that intravenous voriconazole can be utilized in critically ill patients with renal dysfunction requiring di...
What is the current status of trial NCT01101386?
This trial is currently completed. The enrollment target is 10 participants. The study started on 2010-05. Estimated completion is 2012-11.
What conditions does trial NCT01101386 study?
This clinical trial studies the following conditions: Fungal Infection.
What interventions are being tested in trial NCT01101386?
The interventions under investigation include: Voriconazole (DRUG).
Who is sponsoring clinical trial NCT01101386?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01101386 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fungal Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Pharmacogenomics for Better Treatment of Fungal Infections in Cancer
RECRUITING · Phase 2
-
Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
ACTIVE NOT RECRUITING · Phase 3
-
Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (ECMO)
COMPLETED · Phase 1
-
Itraconazole Oral Absorption
COMPLETED · Phase 4
-
CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension
COMPLETED · Phase 2
-
Alternate Day Micafungin: A PK Study in Pediatric Patients
COMPLETED · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00623389 · 10 participants · NA
Evaluation of an Advanced Lower Extremity Neuroprostheses
- NCT01241864 · 10 participants · Phase 2
Islet Transplantation in Type 1 Diabetic Kidney Allograft
- NCT01293214 · 10 participants · NA
Vascularized Composite Allotransplantation for Multiple Extremity Amputations
- NCT01474148 · 10 participants · NA
A Neuroprosthesis for Seated Posture and Balance
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia