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CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension
NCT02734862 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine if intravenous CD101 is safe and effective in the treatment of candidemia and/or invasive candidiasis when compared to caspofungin (followed by oral fluconazole).
Conditions Studied
Interventions
- DRUG Fluconazole
- DRUG Caspofungin
- DRUG oral placebo
- DRUG CD101
- DRUG intravenous placebo
Study Locations (20)
Other
- Jules Bordet Institute — Brussels
- CHU Brugman — Brussels
- Erasme Hospital — Brussels
- UCL Saint-LUC — Brussels
Michigan
- Harper University Hospital — Detroit
- Henry Ford Health System — Detroit
- William Beaumont Hospital — Royal Oak
Alabama
- University of Alabama at Birmingham — Birmingham
California
- University of California - Davis — Davis
Florida
- University of Miami Miller School of Medicine — Miami
Georgia
- Augusta University — Augusta
Massachusetts
- Brigham and Women's Hospital — Boston
Mississippi
- University of Mississippi Medical Center — Jackson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 207 participants |
| Start Date | 2016-07-26 |
| Est. Completion | 2019-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02734862
The ClinicalTrials.gov registry entry for NCT02734862 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 207 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cidara Therapeutics, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Candidemia appearing as the primary indexed condition, and to 5 interventions — of which Fluconazole is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02734862 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Other, Michigan, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02734862 about?
NCT02734862 is a clinical study titled "CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension". The purpose of this study is to determine if intravenous CD101 is safe and effective in the treatment of candidemia and/or invasive candidiasis when compared to caspofungin (followed by oral fluconazole).
What is the current status of trial NCT02734862?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 207 participants. The study started on 2016-07-26. Estimated completion is 2019-07.
What conditions does trial NCT02734862 study?
This clinical trial studies the following conditions: Candidemia, Mycoses, Fungal Infection, Invasive Candidiasis, Fungemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02734862?
The interventions under investigation include: Fluconazole (DRUG), Caspofungin (DRUG), oral placebo (DRUG), CD101 (DRUG), intravenous placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02734862?
This trial is sponsored by Cidara Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02734862 being conducted?
This trial has 20 study locations across Alabama, California, Florida, Georgia, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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