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NCT01095094 · ClinicalTrials.gov registry record · Phase 2
Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma
A Phase 2 study, sponsored by Case Comprehensive Cancer Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 19
- Enrollment target
NCT01095094: Clinical Trial Phase 2 study, sponsored by Case Comprehensive Cancer Center.
NCT01095094 is a Phase 2 study that was terminated before completion, run by Case Comprehensive Cancer Center. The registered enrollment target is 19 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01095094, a Phase 2 study, was terminated before completion, sponsored by Case Comprehensive Cancer Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 19 participants
- Enrollment target
Study Summary
RATIONALE: Ritonavir and lopinavir may stop the growth of gliomas by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well giving ritonavir together with lopinavir works in treating patients with progressive or recurrent high-grade glioma.
Primary Outcome
Number of patients that remained disease free at 6 months from start of treatment.
Interventions
- DRUG ritonavir
- DRUG lopinavir
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2009-01 |
| Est. Completion | 2011-11 |
| Phase | Phase 2 |
Why NCT01095094 stopped before completion
NCT01095094 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which ritonavir is the first listed.
NCT01095094 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01095094 about?
NCT01095094 is a clinical study titled "Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma". RATIONALE: Ritonavir and lopinavir may stop the growth of gliomas by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is studying how well giving ritonavir together with lopinavir works in treating patients with progressive or ...
What is the current status of trial NCT01095094?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2009-01. Estimated completion is 2011-11.
What interventions are being tested in trial NCT01095094?
The interventions under investigation include: ritonavir (DRUG), lopinavir (DRUG).
Who is sponsoring clinical trial NCT01095094?
This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01095094's enrollment target sits among peer trials
19 1894th of 2000 higher than 103 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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