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NCT01094704 · ClinicalTrials.gov registry record · Phase 1

Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis

A Phase 1 study, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT01094704 is a Phase 1 study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 16 participants.

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The verdict

NCT01094704, a Phase 1 study, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

Direct measurement of mucociliary and cough clearance (MCC/CC) has been used as a biomarker in cystic fibrosis (CF). Additional knowledge of the performance of this biomarker is needed to inform exploratory clinical trial design in support of programs to develop new inhaled therapies for CF. We hypothesize that MCC/CC measurements can be used to determine the durability of action of agents like hypertonic saline (HS) which increase epithelial lining fluid height.

Interventions

  • DRUG sodium chloride (7%)

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2009-11
Est. Completion 2010-05
Phase Phase 1

What the Registry Record Tells You About NCT01094704

The ClinicalTrials.gov registry entry for NCT01094704 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which sodium chloride (7%) is the first listed.

NCT01094704 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01094704 about?

NCT01094704 is a clinical study titled "Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis". Direct measurement of mucociliary and cough clearance (MCC/CC) has been used as a biomarker in cystic fibrosis (CF). Additional knowledge of the performance of this biomarker is needed to inform exploratory clinical trial design in support of programs to develop new inhaled therapies for CF. We hypo...

What is the current status of trial NCT01094704?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2009-11. Estimated completion is 2010-05.

What interventions are being tested in trial NCT01094704?

The interventions under investigation include: sodium chloride (7%) (DRUG).

Who is sponsoring clinical trial NCT01094704?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.