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NCT01092065 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety of AFQ056 When Combined With Increased Doses of L-dopa in Parkinson's Disease Patients With Moderate-severe L-dopa Induced Dyskinesia

A Phase 2 study of Parkinson's Disease, sponsored by Novartis.

Completed
Registry status
Phase 2
Development phase
23
Enrollment target
4
Study locations

NCT01092065 is a Phase 2 study of Parkinson's Disease that has completed, run by Novartis. The registered enrollment target is 23 participants, below the 642-participant average among 156 other Parkinson's Disease trials with a reported enrollment target (96% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT01092065, a Phase 2 study of Parkinson's Disease, has completed, sponsored by Novartis.

COMPLETED
Registry status
Phase 2
Development phase
23 participants
Enrollment target
4
Study locations

Study Summary

This Phase IIb exploratory study is designed to determine whether AFQ056 is safe and effective and whether it can increase the therapeutic window of L-dopa in patients whose control of their Parkinson's Disease symptoms is limited by the development of dyskinesia induced by use of L-dopa.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG AFQ056 with L-dopa

Study Locations (4)

California

  • The Parkinsons Institute - Sunnyvale

Colorado

  • Colorado Neurological Institute - Englewood

Indiana

  • Indiana University School of Medicine - Indianapolis

Kansas

  • University of Kansas Medical Center - Parkinson's Disease and Movement Disorders Center - Kansas City

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2010-03
Est. Completion 2011-07
Phase Phase 2

Sponsor

Novartis

265 total trials

What the Registry Record Tells You About NCT01092065

The ClinicalTrials.gov registry entry for NCT01092065 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 642-participant average among 156 other Parkinson's Disease trials with a reported enrollment target (96% lower). The listed sponsor is Novartis, which has 265 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Parkinson's Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01092065 reports 4 study locations spanning 4 distinct geographic areas - top geographies include California, Colorado, Indiana.

Frequently Asked Questions

What is clinical trial NCT01092065 about?

NCT01092065 is a clinical study titled "Efficacy and Safety of AFQ056 When Combined With Increased Doses of L-dopa in Parkinson's Disease Patients With Moderate-severe L-dopa Induced Dyskinesia". This Phase IIb exploratory study is designed to determine whether AFQ056 is safe and effective and whether it can increase the therapeutic window of L-dopa in patients whose control of their Parkinson's Disease symptoms is limited by the development of dyskinesia induced by use of L-dopa.

What is the current status of trial NCT01092065?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2010-03. Estimated completion is 2011-07.

What conditions does trial NCT01092065 study?

This clinical trial studies the following conditions: Parkinson's Disease.

What interventions are being tested in trial NCT01092065?

The interventions under investigation include: Placebo (DRUG), AFQ056 with L-dopa (DRUG).

Who is sponsoring clinical trial NCT01092065?

This trial is sponsored by Novartis, which has 265 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01092065 being conducted?

This trial has 4 study locations across California, Colorado, Indiana, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.