Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01087905 · ClinicalTrials.gov registry record · Phase 4

Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines

A Phase 4 study of Smoking Cessation and Smoking, sponsored by University of Wisconsin, Madison.

Completed
Registry status
Phase 4
Development phase
987
Enrollment target
2
Study locations

NCT01087905: Completed Phase 4 study of Smoking Cessation and Smoking, sponsored by University of Wisconsin, Madison.

NCT01087905 is a Phase 4 study of Smoking Cessation and Smoking that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 987 participants, above the 469-participant average among 188 other Smoking Cessation trials with a reported enrollment target (110% higher). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01087905, a Phase 4 study of Smoking Cessation and Smoking, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
Phase 4
Development phase
987 participants
Enrollment target
2
Study locations

Study Summary

Research shows that smoking cessation is the most significant preventable health behavior change that a person can make to lower cancer risk. In addition, telephone quitlines are an effective, science-based smoking cessation treatment that is universally accessible to smokers in the U.S. However, little research has explored promising approaches that could increase quitline use, improve quit rates, and inform resource allocation for quitline services. The proposed study will test three promising enhancements to the standard quitline treatment that typically consists of counseling and, possibly 2 weeks of a NRT medication. These enhancements are: 1) combination nicotine replacement therapy as recommended by the United States Public Health Service Clinical Practice Guideline on Treating Tobacco Use and Dependence; 2) extended duration of cessation medication use; and 3) an innovative counseling addition - cognitive medication adherence counseling - to optimize adherence to cessation medication. In addition, the cost-effectiveness of each intervention will be calculated. The findings of the proposed research have broad potential application and relevance to state quitlines, quitline service providers, and other purchasers of quitline services such as employers and insurers. Additionally, the study findings can potentially inform other telephone health behavior counseling programs.

Primary Outcome

Self-reported total abstinence from any tobacco use (even a single puff) for the seven days preceding the target follow-up day.

Interventions

  • DRUG Nicotine gum
  • DRUG Nicotine patch
  • BEHAVIORAL CMAC

Study Locations (2)

Washington

  • Wisconsin Tobacco Quit Line (service provided by Free & Clear, Inc.) - Seattle

Wisconsin

  • University of Wisconsin Center for Tobacco Research and Intervention - Madison

Trial Details

FieldValue
Enrollment Target 987 participants
Start Date 2010-04
Est. Completion 2011-11
Phase Phase 4
University of Wisconsin, Madison

1,039 total trials

What the finished NCT01087905 record still lists

NCT01087905 is an interventional study that assigns participants to a tested intervention. The registered 987 participants enrollment target is mid-sized for trials with a published cap, above the 469-participant average among 188 other Smoking Cessation trials with a reported enrollment target (110% higher).

The record links to 2 conditions, with Smoking Cessation appearing as the primary indexed condition, and to 3 interventions - of which Nicotine gum is the first listed.

NCT01087905 reports a single indexed study location in Washington, Wisconsin.

Frequently Asked Questions

What is clinical trial NCT01087905 about?

NCT01087905 is a clinical study titled "Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines". Research shows that smoking cessation is the most significant preventable health behavior change that a person can make to lower cancer risk. In addition, telephone quitlines are an effective, science-based smoking cessation treatment that is universally accessible to smokers in the U.S. However, li...

What is the current status of trial NCT01087905?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 987 participants. The study started on 2010-04. Estimated completion is 2011-11.

What conditions does trial NCT01087905 study?

This clinical trial studies the following conditions: Smoking Cessation, Smoking.

What interventions are being tested in trial NCT01087905?

The interventions under investigation include: Nicotine gum (DRUG), Nicotine patch (DRUG), CMAC (BEHAVIORAL).

Who is sponsoring clinical trial NCT01087905?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01087905 being conducted?

This trial has 2 study locations across Washington, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Smoking Cessation

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01087905's enrollment target sits among peer trials

987 24th of 188 higher than 165 of 188 other Smoking Cessation trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Smoking Cessation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05079841 · 988 participants · Phase 4

    The Stimulation To Induce Mothers Study

  • NCT05441709 · 990 participants · NA

    Furthering Equity Through Infant Feeding EDucation and Support

  • NCT06340646 · 990 participants · NA

    Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

  • NCT06878261 · 990 participants · Phase 3

    A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01087905, the US trial registry maintained by the National Library of Medicine. NCT01087905 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.