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NCT01084057 · ClinicalTrials.gov registry record · Phase 1

Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast Cancer

A Phase 1 study, sponsored by City of Hope Medical Center.

Completed
Registry status
Phase 1
Development phase
56
Enrollment target

NCT01084057 is a Phase 1 study that has completed, run by City of Hope Medical Center. The registered enrollment target is 56 participants.

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The verdict

NCT01084057, a Phase 1 study, has completed, sponsored by City of Hope Medical Center.

COMPLETED
Registry status
Phase 1
Development phase
56 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as ixabepilone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing or by stopping them from spreading. Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving ixabepilone together with vorinostat may kill more tumor cells. PURPOSE: This randomized phase I trial is studying the side effects, best way to give, and best dose of vorinostat when given together with ixabepilone in treating patients with breast cancer that has spread to another place in the body.

Interventions

  • OTHER laboratory biomarker analysis
  • DRUG vorinostat
  • OTHER pharmacological study
  • DRUG ixabepilone

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2010-05-17
Est. Completion 2019-09-27
Phase Phase 1

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT01084057

The ClinicalTrials.gov registry entry for NCT01084057 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT01084057 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01084057 about?

NCT01084057 is a clinical study titled "Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as ixabepilone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing or by stopping them from spreading. Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed...

What is the current status of trial NCT01084057?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2010-05-17. Estimated completion is 2019-09-27.

What interventions are being tested in trial NCT01084057?

The interventions under investigation include: laboratory biomarker analysis (OTHER), vorinostat (DRUG), pharmacological study (OTHER), ixabepilone (DRUG).

Who is sponsoring clinical trial NCT01084057?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.