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NCT01076543 · ClinicalTrials.gov registry record · Phase 1

Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
110
Enrollment target

NCT01076543: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT01076543 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 110 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01076543, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
110 participants
Enrollment target

Study Summary

This phase I/II trial studies the side effects and the best dose of lenalidomide when given together with temsirolimus and to see how well it works in treating patients with Hodgkin lymphoma or non-Hodgkin lymphoma that has come back after a period of improvement or is not responding to treatment. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Lenalidomide may also stop the growth of Hodgkin lymphoma or non-Hodgkin lymphoma by blocking blood flow to the cancer. Temsirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving lenalidomide together with temsirolimus may kill more cancer cells.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Lenalidomide
  • DRUG Temsirolimus

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2010-04-15
Est. Completion 2018-09-30
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01076543

The ClinicalTrials.gov registry entry for NCT01076543 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT01076543 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01076543 about?

NCT01076543 is a clinical study titled "Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma". This phase I/II trial studies the side effects and the best dose of lenalidomide when given together with temsirolimus and to see how well it works in treating patients with Hodgkin lymphoma or non-Hodgkin lymphoma that has come back after a period of improvement or is not responding to treatment. B...

What is the current status of trial NCT01076543?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 110 participants. The study started on 2010-04-15. Estimated completion is 2018-09-30.

What interventions are being tested in trial NCT01076543?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Lenalidomide (DRUG), Temsirolimus (DRUG).

Who is sponsoring clinical trial NCT01076543?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.