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NCT01075113 · ClinicalTrials.gov registry record · Phase 1
Sorafenib and Vorinostat in Treating Patients With Advanced Liver Cancer
A Phase 1 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT01075113: Completed Phase 1 study, sponsored by Virginia Commonwealth University.
NCT01075113 is a Phase 1 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01075113, a Phase 1 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This phase I trial is studying the side effects and best dose of vorinostat when given together with sorafenib tosylate in treating patients with advanced liver cancer. Sorafenib tosylate and vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow to the tumor.
Primary Outcome
Identify the maximum tolerated dose of the combination regimen of vorinostat and sorafenib to study further for efficacy of treatment for hepatocellular carcinoma
Interventions
- DRUG vorinostat
- DRUG sorafenib tosylate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2010-08-10 |
| Est. Completion | 2019-07-18 |
| Phase | Phase 1 |
What the finished NCT01075113 record still lists
NCT01075113 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 2 interventions - of which vorinostat is the first listed.
NCT01075113 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01075113 about?
NCT01075113 is a clinical study titled "Sorafenib and Vorinostat in Treating Patients With Advanced Liver Cancer". This phase I trial is studying the side effects and best dose of vorinostat when given together with sorafenib tosylate in treating patients with advanced liver cancer. Sorafenib tosylate and vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by b...
What is the current status of trial NCT01075113?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2010-08-10. Estimated completion is 2019-07-18.
What interventions are being tested in trial NCT01075113?
The interventions under investigation include: vorinostat (DRUG), sorafenib tosylate (DRUG).
Who is sponsoring clinical trial NCT01075113?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01075113's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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