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NCT01074229 · ClinicalTrials.gov registry record · NA
Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy
A NA study of Postoperative Pain, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT01074229: Completed NA study of Postoperative Pain, sponsored by Northwestern University.
NCT01074229 is a NA study of Postoperative Pain that has completed, run by Northwestern University. The registered enrollment target is 75 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (68% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01074229, a NA study of Postoperative Pain, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the dorsal rami of L1-3 are blocked with an injection of local anesthetic between the internal oblique abdominal muscle (IOAM) and the transverse abdominal muscle(TAM)This technique allows sensory blockade of the anterolateral abdominal wall via local anesthetic deposition superficial to the transversus abdominis muscle. It was first described by McDonnell et al. as a landmark technique to provide analgesia for lower abdominal surgery. Hebbart et al. subsequently described an ultrasound guided technique for the TAP block which they named posterior TAP block. The ultrasound allows identification of the external oblique abdominal muscles (EOAM),IOAM and TAM. Previous studies about ultrasound -guided regional anesthetic techniques suggest improved block quality and safety, which is primarily due to direct visualization of the relevant anatomy, the tip of the needle, and the spread of the local anesthetics. Clinical trials of the single shot posterior TAP block have shown a significant reduction in morphine consumption during the first 24-36 hours after surgery. More recently, El-dawlatly et al. demonstrated that ultrasound guided TAP block in patients undergoing laparoscopic cholecystectomy reduced perioperative opioid consumption by more than 50%. This is the first study to evaluate the effect of TAP block in the quality of recovery in patients undergoing laparoscopic hysterectomy and may help the pathway to make this an outpatient procedure.
Primary Outcome
QoR40 on the day after surgery. Quality of recovery is based on a score of 40-200. 40 being a poor recovery and 200 being a good recovery score.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Drug .5% Ropivacaine
- DRUG 20 cc of 0.25% ropivacaine
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2010-03 |
| Est. Completion | 2010-10 |
| Phase | NA |
What the finished NCT01074229 record still lists
NCT01074229 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (68% lower).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT01074229 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01074229 about?
NCT01074229 is a clinical study titled "Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy". The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the dorsal rami of L1-3 are blocked with an injection of local anesthetic betw...
What is the current status of trial NCT01074229?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2010-03. Estimated completion is 2010-10.
What conditions does trial NCT01074229 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT01074229?
The interventions under investigation include: Placebo (DRUG), Drug .5% Ropivacaine (DRUG), 20 cc of 0.25% ropivacaine (DRUG).
Who is sponsoring clinical trial NCT01074229?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01074229 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01074229's enrollment target sits among peer trials
75 77th of 120 higher than 41 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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