Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01074229 · ClinicalTrials.gov registry record · NA
Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy
A NA study of Postoperative Pain, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT01074229 is a NA study of Postoperative Pain that has completed, run by Northwestern University. The registered enrollment target is 75 participants, below the 230-participant average among 63 other Postoperative Pain trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01074229, a NA study of Postoperative Pain, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the dorsal rami of L1-3 are blocked with an injection of local anesthetic between the internal oblique abdominal muscle (IOAM) and the transverse abdominal muscle(TAM)This technique allows sensory blockade of the anterolateral abdominal wall via local anesthetic deposition superficial to the transversus abdominis muscle. It was first described by McDonnell et al. as a landmark technique to provide analgesia for lower abdominal surgery. Hebbart et al. subsequently described an ultrasound guided technique for the TAP block which they named posterior TAP block. The ultrasound allows identification of the external oblique abdominal muscles (EOAM),IOAM and TAM. Previous studies about ultrasound -guided regional anesthetic techniques suggest improved block quality and safety, which is primarily due to direct visualization of the relevant anatomy, the tip of the needle, and the spread of the local anesthetics. Clinical trials of the single shot posterior TAP block have shown a significant reduction in morphine consumption during the first 24-36 hours after surgery. More recently, El-dawlatly et al. demonstrated that ultrasound guided TAP block in patients undergoing laparoscopic cholecystectomy reduced perioperative opioid consumption by more than 50%. This is the first study to evaluate the effect of TAP block in the quality of recovery in patients undergoing laparoscopic hysterectomy and may help the pathway to make this an outpatient procedure.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Drug .5% Ropivacaine
- DRUG 20 cc of 0.25% ropivacaine
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2010-03 |
| Est. Completion | 2010-10 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01074229
The ClinicalTrials.gov registry entry for NCT01074229 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 75 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 230-participant average among 63 other Postoperative Pain trials with a reported enrollment target (67% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT01074229 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT01074229 about?
NCT01074229 is a clinical study titled "Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy". The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the dorsal rami of L1-3 are blocked with an injection of local anesthetic betw...
What is the current status of trial NCT01074229?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2010-03. Estimated completion is 2010-10.
What conditions does trial NCT01074229 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT01074229?
The interventions under investigation include: Placebo (DRUG), Drug .5% Ropivacaine (DRUG), 20 cc of 0.25% ropivacaine (DRUG).
Who is sponsoring clinical trial NCT01074229?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01074229 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery
RECRUITING · NA
-
Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery
RECRUITING · NA
-
Rectus Sheath Block in Cardiac Surgery
RECRUITING · NA
-
Postoperative VR for Recovery After Bariatric Surgery
ACTIVE NOT RECRUITING · NA
-
The Perioperative Pain Self-Management Program Trial
ACTIVE NOT RECRUITING · NA
-
PENG Block for Arthroscopic Hip Surgery
COMPLETED · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.