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NCT01058408 · ClinicalTrials.gov registry record · Phase 1

RAD001 With Weekly Cisplatin and Radiation Therapy in Patients With Locally Advanced Head and Neck Cancer

A Phase 1 study, sponsored by Dana-Farber Cancer Institute.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT01058408 is a Phase 1 study that was terminated before completion, run by Dana-Farber Cancer Institute. The registered enrollment target is 3 participants.

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The verdict

NCT01058408, a Phase 1 study, was terminated before completion, sponsored by Dana-Farber Cancer Institute.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

RAD001 is approved by the U.S Food and Drug Administration (FDA) to treat advanced kidney cancer. This drug has also been used in other research studies to evaluate its effectiveness in other cancers. Information from these research studies suggests that RAD001 may help to decrease the growth and development of tumor cells by reducing the blood supply that tumors need to grow. In this research study, we are trying to determine the safety of RAD001 when given to people with locally advanced head and neck cancer in combination with cisplatin and radiation. We are also looking for the highest dose of RAD001 that can be given to people safely.

Interventions

  • DRUG cisplatin
  • DRUG RAD001
  • RADIATION Intensity modulated radiotherapy

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2010-02
Phase Phase 1

Sponsor

Dana-Farber Cancer Institute

781 total trials

What the Registry Record Tells You About NCT01058408

The ClinicalTrials.gov registry entry for NCT01058408 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dana-Farber Cancer Institute, which has 781 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which cisplatin is the first listed.

NCT01058408 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01058408 about?

NCT01058408 is a clinical study titled "RAD001 With Weekly Cisplatin and Radiation Therapy in Patients With Locally Advanced Head and Neck Cancer". RAD001 is approved by the U.S Food and Drug Administration (FDA) to treat advanced kidney cancer. This drug has also been used in other research studies to evaluate its effectiveness in other cancers. Information from these research studies suggests that RAD001 may help to decrease the growth and de...

What is the current status of trial NCT01058408?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2010-02.

What interventions are being tested in trial NCT01058408?

The interventions under investigation include: cisplatin (DRUG), RAD001 (DRUG), Intensity modulated radiotherapy (RADIATION).

Who is sponsoring clinical trial NCT01058408?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.