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NCT01055184 · ClinicalTrials.gov registry record · Phase 1

Effects of Age on Response to the 2009 H1N1 Virus Vaccine

A Phase 1 study, sponsored by University of Rochester.

Completed
Registry status
Phase 1
Development phase
34
Enrollment target

NCT01055184: Completed Phase 1 study, sponsored by University of Rochester.

NCT01055184 is a Phase 1 study that has completed, run by University of Rochester. The registered enrollment target is 34 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01055184, a Phase 1 study, has completed, sponsored by University of Rochester.

COMPLETED
Registry status
Phase 1
Development phase
34 participants
Enrollment target

Study Summary

Unlike most influenza viruses, the 2009 H1N1 virus has affected people between 5 and 40 years old more often than people 60 years old or older. It may be that older people have had greater exposure to previous strains of H1N1 influenza, and this previous exposure protects them from infection. This study will examine how older people respond to a version of the H1N1 virus vaccine that includes a live, noninfectious version of the virus.

Primary Outcome

number of participants who shed virus above the limit of detection at any timepoint after vaccine. The limit of detection is 0.5 tissue culture infectious doses per mL of nasal wash.

Interventions

  • BIOLOGICAL 2009 H1N1 Virus Vaccine

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2010-03
Phase Phase 1
University of Rochester

636 total trials

What the finished NCT01055184 record still lists

NCT01055184 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower).

The record links to 0 conditions, and to 1 intervention - of which 2009 H1N1 Virus Vaccine is the first listed.

NCT01055184 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01055184 about?

NCT01055184 is a clinical study titled "Effects of Age on Response to the 2009 H1N1 Virus Vaccine". Unlike most influenza viruses, the 2009 H1N1 virus has affected people between 5 and 40 years old more often than people 60 years old or older. It may be that older people have had greater exposure to previous strains of H1N1 influenza, and this previous exposure protects them from infection. This s...

What is the current status of trial NCT01055184?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2010-03.

What interventions are being tested in trial NCT01055184?

The interventions under investigation include: 2009 H1N1 Virus Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT01055184?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01055184's enrollment target sits among peer trials

34 1273rd of 2000 higher than 721 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01055184, the US trial registry maintained by the National Library of Medicine. NCT01055184 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.