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NCT01052038 · ClinicalTrials.gov registry record · Phase 4

Post Operative Sore Throat and Dexamethasone

A Phase 4 study, sponsored by Northwestern University.

Completed
Registry status
Phase 4
Development phase
120
Enrollment target

NCT01052038: Completed Phase 4 study, sponsored by Northwestern University.

NCT01052038 is a Phase 4 study that has completed, run by Northwestern University. The registered enrollment target is 120 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01052038, a Phase 4 study, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
Phase 4
Development phase
120 participants
Enrollment target

Study Summary

Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions. There are several factors that have been shown to contribute to postoperative sore throat such as patient related factors, type of anesthesia and type of surgery. Corticosteroids are also commonly used in the perioperative period to potentiate analgesics and as antiemetics. The preoperative administration of dexamethasone can decrease the incidence and severity of postoperative sore throat which is rated by patients as one of the most undesirable outcomes in the postoperative period.

Primary Outcome

The reported score for sore throat on a 1 to 5 scale where 1 is a severe sore throat and 5 is no sore throat. This evaluation was made by investigator initiated phone conversation at 24 hours following surgery.

Interventions

  • DRUG Placebo administration
  • DRUG Dexamethasone 0.05mg/kr administration
  • DRUG Dexamethasone 0.1mg/kg

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2010-01
Est. Completion 2010-09
Phase Phase 4
Northwestern University

1,209 total trials

What the finished NCT01052038 record still lists

NCT01052038 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo administration is the first listed.

NCT01052038 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01052038 about?

NCT01052038 is a clinical study titled "Post Operative Sore Throat and Dexamethasone". Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions. There are several factors that have been shown to contribute to postoperative sor...

What is the current status of trial NCT01052038?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2010-01. Estimated completion is 2010-09.

What interventions are being tested in trial NCT01052038?

The interventions under investigation include: Placebo administration (DRUG), Dexamethasone 0.05mg/kr administration (DRUG), Dexamethasone 0.1mg/kg (DRUG).

Who is sponsoring clinical trial NCT01052038?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01052038's enrollment target sits among peer trials

120 673rd of 2000 higher than 1,289 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01052038, the US trial registry maintained by the National Library of Medicine. NCT01052038 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.