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NCT01045928 · ClinicalTrials.gov registry record · Phase 1

Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma

A Phase 1 study, sponsored by Case Comprehensive Cancer Center.

Terminated
Registry status
Phase 1
Development phase
5
Enrollment target

NCT01045928 is a Phase 1 study that was terminated before completion, run by Case Comprehensive Cancer Center. The registered enrollment target is 5 participants.

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The verdict

NCT01045928, a Phase 1 study, was terminated before completion, sponsored by Case Comprehensive Cancer Center.

TERMINATED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

RATIONALE: Lenalidomide may stop the growth of cancer by blocking blood flow to the tumor. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving lenalidomide together with rituximab may be an effective treatment for B-cell non-Hodgkin lymphoma. PURPOSE: This phase I/II trial is studying the side effects and best dose of lenalidomide when given together with rituximab as maintenance therapy in treating patients with B-cell non-Hodgkin lymphoma.

Interventions

  • BIOLOGICAL rituximab
  • GENETIC polymerase chain reaction
  • DRUG lenalidomide
  • GENETIC polymorphism analysis
  • GENETIC nucleic acid sequencing

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2010-01
Est. Completion 2012-03
Phase Phase 1

Sponsor

Case Comprehensive Cancer Center

407 total trials

What the Registry Record Tells You About NCT01045928

The ClinicalTrials.gov registry entry for NCT01045928 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Case Comprehensive Cancer Center, which has 407 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which rituximab is the first listed.

NCT01045928 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01045928 about?

NCT01045928 is a clinical study titled "Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma". RATIONALE: Lenalidomide may stop the growth of cancer by blocking blood flow to the tumor. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killi...

What is the current status of trial NCT01045928?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2010-01. Estimated completion is 2012-03.

What interventions are being tested in trial NCT01045928?

The interventions under investigation include: rituximab (BIOLOGICAL), polymerase chain reaction (GENETIC), lenalidomide (DRUG), polymorphism analysis (GENETIC), nucleic acid sequencing (GENETIC).

Who is sponsoring clinical trial NCT01045928?

This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.