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NCT01045694 · ClinicalTrials.gov registry record · Phase 4
Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint
A Phase 4 study, sponsored by University of Missouri-Columbia.
- Terminated
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
NCT01045694: Clinical Trial Phase 4 study, sponsored by University of Missouri-Columbia.
NCT01045694 is a Phase 4 study that was terminated before completion, run by University of Missouri-Columbia. The registered enrollment target is 8 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01045694, a Phase 4 study, was terminated before completion, sponsored by University of Missouri-Columbia.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
Study Summary
Basal arthritis of the thumb is a common condition with increased prevalence in post-menopausal women, obese persons, and the elderly. Surgical options are varied and efficacious, but not all patients are candidates for surgery. The successes and pitfalls of previous, similar trials are carefully considered in the creation of our own. Though steroid injection is the standard of care in basal joint arthritis, current data does not support its efficacy beyond placebo effect. No trial has yet examined the efficacy of botulinum toxin type A (BTX-A) injection into the basal thumb joint nor compared it to steroid. Since efficacy of steroid is questionable at best, our hope is that BTX-A injection of the basal joint might be the next great tool in treating this common, debilitating disease.
Interventions
- DRUG Lidocaine
- DRUG Botulinum Toxin Type A
- DRUG Steroid - Triamcinolone Acetonide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2011-03 |
| Est. Completion | 2015-10 |
| Phase | Phase 4 |
Why NCT01045694 stopped before completion
NCT01045694 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 3 interventions - of which Lidocaine is the first listed.
NCT01045694 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01045694 about?
NCT01045694 is a clinical study titled "Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint". Basal arthritis of the thumb is a common condition with increased prevalence in post-menopausal women, obese persons, and the elderly. Surgical options are varied and efficacious, but not all patients are candidates for surgery. The successes and pitfalls of previous, similar trials are carefully co...
What is the current status of trial NCT01045694?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2011-03. Estimated completion is 2015-10.
What interventions are being tested in trial NCT01045694?
The interventions under investigation include: Lidocaine (DRUG), Botulinum Toxin Type A (DRUG), Steroid - Triamcinolone Acetonide (DRUG).
Who is sponsoring clinical trial NCT01045694?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01045694's enrollment target sits among peer trials
8 1972nd of 2000 higher than 20 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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