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NCT01024231 · ClinicalTrials.gov registry record · Phase 1
Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
A Phase 1 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 127
- Enrollment target
NCT01024231: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.
NCT01024231 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 127 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (112% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01024231, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 127 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the safety and tolerability of treatment with BMS-936558 (MDX-1106) in combination with Ipilimumab (BMS-734016) when given at the same time or as a sequenced regimen in subjects with unresectable Stage III or Stage IV malignant melanoma (MEL)
Primary Outcome
incidence of all cause and treatment related adverse events
Interventions
- DRUG Ipilimumab
- DRUG BMS-936558 (MDX1106-04)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 127 participants |
| Start Date | 2009-12-14 |
| Est. Completion | 2019-04-01 |
| Phase | Phase 1 |
What the finished NCT01024231 record still lists
NCT01024231 is an interventional study that assigns participants to a tested intervention. The registered 127 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (112% higher).
The record links to 0 conditions, and to 2 interventions - of which Ipilimumab is the first listed.
NCT01024231 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01024231 about?
NCT01024231 is a clinical study titled "Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma". The purpose of this study is to determine the safety and tolerability of treatment with BMS-936558 (MDX-1106) in combination with Ipilimumab (BMS-734016) when given at the same time or as a sequenced regimen in subjects with unresectable Stage III or Stage IV malignant melanoma (MEL)
What is the current status of trial NCT01024231?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 127 participants. The study started on 2009-12-14. Estimated completion is 2019-04-01.
What interventions are being tested in trial NCT01024231?
The interventions under investigation include: Ipilimumab (DRUG), BMS-936558 (MDX1106-04) (DRUG).
Who is sponsoring clinical trial NCT01024231?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01024231's enrollment target sits among peer trials
127 459th of 2000 higher than 1,540 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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