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NCT01021072 · ClinicalTrials.gov registry record · Phase 1
A First in Man Study of MABp1 in Patients With Advanced Cancers
A Phase 1 study, sponsored by Janssen Research & Development.
- Completed
- Registry status
- Phase 1
- Development phase
- 52
- Enrollment target
NCT01021072: Completed Phase 1 study, sponsored by Janssen Research & Development.
NCT01021072 is a Phase 1 study that has completed, run by Janssen Research & Development. The registered enrollment target is 52 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01021072, a Phase 1 study, has completed, sponsored by Janssen Research & Development.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 52 participants
- Enrollment target
Study Summary
The purpose of this study is to block interleukin-1 alpha activity with a True Human monoclonal antibody, thus interrupting the inflammatory response that supports tumor growth/metastasis and which drives the cachexic process. An adaptive design will be employed which will allow for the exploration of different dosing regimens, as well as tumor types that show preliminary evidence of efficacy.
Interventions
- DRUG MABp1
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2010-03-31 |
| Est. Completion | 2013-08-31 |
| Phase | Phase 1 |
What the finished NCT01021072 record still lists
NCT01021072 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% lower).
The record links to 0 conditions, and to 1 intervention - of which MABp1 is the first listed.
NCT01021072 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01021072 about?
NCT01021072 is a clinical study titled "A First in Man Study of MABp1 in Patients With Advanced Cancers". The purpose of this study is to block interleukin-1 alpha activity with a True Human monoclonal antibody, thus interrupting the inflammatory response that supports tumor growth/metastasis and which drives the cachexic process. An adaptive design will be employed which will allow for the exploration...
What is the current status of trial NCT01021072?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2010-03-31. Estimated completion is 2013-08-31.
What interventions are being tested in trial NCT01021072?
The interventions under investigation include: MABp1 (DRUG).
Who is sponsoring clinical trial NCT01021072?
This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01021072's enrollment target sits among peer trials
52 956th of 2000 higher than 1,032 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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